Results 91 to 100 of about 35,863 (248)
Case Reports in Neurological Medicine, 2018 Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system.
Sira Carrasco García de León +3 more
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Aggregate, Volume 7, Issue 2, February 2026.Protein aggregation drives diverse degenerative diseases, yet its molecular origins are difficult to predict. SKALE uses interpretable machine learning to link sequence, structure, and dynamics, revealing how local structural weakening triggers aggregation.
Wei Xuan Wilson Loo +7 more
wiley +1 more source
Association of genetic predisposition to dyslipidemia and physical activity with incident dementia
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION The association between genetic predisposition to dyslipidemia and dementia risk is inconsistent. It remains unknown whether a physically active lifestyle is associated with a lower dementia risk across different levels of this genetic predisposition.
Yumei Liang +5 more
wiley +1 more source
Sporadic Creutzfeldt‐Jakob disease: A case report and review of literature
Clinical Case Reports, 2020 Creutzfeldt‐Jakob Disease is a rare neurodegenerative disease and earlier diagnosis is usually difficult. Combining clinical features with electroencephalogram, laboratory parameters, and neuroimaging findings will facilitate the diagnosis.
Rajeev Ojha +5 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION Proteins interacting with amyloid beta (Aβ) fibrils could be key to plaque formation in Alzheimer's disease (AD) and represent potential biomarkers and therapeutic targets. Previous proteomic studies using microdissected plaques might have captured non‐specific components rather than true Aβ interactors.
Ana Montero‐Calle +10 more
wiley +1 more source
Determination of neuronal antibodies in suspected and definite Creutzfeldt-Jakob disease [PDF]
, 2018 IMPORTANCE Creutzfeldt-Jakob disease (CJD) and autoimmune encephalitis with antibodies against neuronal surface antigens (NSA-abs) may present with similar clinical features. Establishing the correct diagnosis has practical implications in the management
Bernabé, Reyes +12 more
core +1 more source
Review: Creutzfeldt‐Jakob Disease
Brain Pathology, 1996 The clinicopathological spectrum of Creutzfeldt‐Jakob disease has recently been extended by the identification of an apparently new variant of this disorder in the UK. The hypothesis that this new disorder is causally related to the transmissible agent responsible for bovine spongiform encephalopathy has prompted re‐evaluation of the relationships ...
openaire +2 more sources
Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner. [PDF]
, 2017 Prions are infectious agents that cause neurodegenerative diseases such as Creutzfeldt-Jakob disease (CJD). The absence of a human cell culture model that replicates human prions has hampered prion disease research for decades.
Alibhai, James +9 more
core +1 more source
Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]
, 2008 The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Jacobs, J.G. +3 more
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Sporadic Creutzfeldt-Jakob disease: Clinical, pathological and molecular study [PDF]
Revista Ciencias de la Salud, 2008 phalopathiesare neurodegenerative diseasescaused by abnormal accumulation of pathogenicisoform the prion protein, which induces theformation of conglomerates protein resistantto degradation.
Victoria Eugenia Villegas +2 more
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