Endogenous Viral Etiology of Prion Diseases [PDF]
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease in cattle, and scrapie in sheep. This paper
Claudiu I. Bandea
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Complicated symptomatology and diagnosis of Creuzfeld-Jakob disease on a basis of clinical case
Creutzfeldt-Jakob disease (CJD) is a rare condition. In this study we describe the diagnosis of the disease in a 73-year old female, presenting dementia. Diagnostic tests unveiled characteristic features of CJD. The diagnosis of CJD was confirmed. It is
Marta Jurga +9 more
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A survey and a molecular dynamics study on the (central) hydrophobic region of prion proteins
Prion diseases are invariably fatal neurodegenerative diseases that affect humans and animals. Unlike most other amyloid forming neurodegenerative diseases, these can be highly infectious. Prion diseases occur in a variety of species.
Wang, Feng, Zhang, Jiapu
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Variant Creutzfeldt-Jakob disease
Variant Creutzfeldt-Jakob disease is caused by the transmission of bovine spongiform encephalopathy to humans. The clinical and investigative features of variant CJD are relatively distinct from sporadic CJD. The number of cases of vCJD are increasing with time in the UK, but the total future number of cases of vCJD is uncertain.
openaire +4 more sources
New Variant Creutzfeldt-Jakob Disease
New variant Creutzfeldt-Jakob disease is a novel human spongiform encephalopathy with a consistent clinico-pathological phenotype. Epidemiological evidence indicates that this disease is occurring almost exclusively in the UK, where there has been an epidemic of spongiform encephalopathy in the cattle population.
openaire +3 more sources
É apresentado caso sugestivo de doença de Creutzfeldt-Jakob em adulto jovem. O estudo anátomo-patológico revelou alteração difusa no córtice cerebral, núcleos da base e medula, constituídas por degeneração neuronal, gliose, espongiose e infiltração ...
Osvaldo J. M. Nascimento +1 more
doaj
Does Improvement in Case Ascertainment Explain the Increase in Sporadic Creutzfeldt-Jakob Disease Since 1970 in the United Kingdom? [PDF]
The aim of this study was to quantify the improvements in case ascertainment which are considered to explain the rise in the incidence of sporadic Creutzfeldt-Jakob disease.
Cohen, Carine H.
core
Cellular distribution of the prion protein in palatine tonsils of mule deer (Odocoileus hemionus) and Rocky Mountain elk (Cervus elaphus nelsoni) [PDF]
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects members of the Cervidae family, including deer (Odocoileus spp.), elk (Cervus Canadensis spp.), and moose (Alces alces spp.).
Belden, E. Lee +2 more
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Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease [PDF]
To validate the provisional findings of a number of smaller studies and explore additional determinants of characteristic diagnostic investigation results across the entire clinical spectrum of sporadic Creutzfeldt-Jakob disease (CJD), an international ...
Almonti, S. +25 more
core
Variant Creutzfeldt-Jakob disease surveillance in Spain, 1993-2021. [PDF]
De Pedro-Cuesta J +4 more
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