Results 111 to 120 of about 22,988 (222)

Pros and cons of a prion-like pathogenesis in Parkinson's disease [PDF]

, 2011
Background: Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder which affects widespread areas of the brainstem, basal ganglia and cerebral cortex.
Chapman Joab, Hilker, Ruediger, Brotchie, Jonathan M, Hilker, Rüdiger, Hilker Ruediger, Brotchie, Jonathan M., Joab Chapman, Ruediger Hilker, Chapman, Joab, Jonathan M Brotchie, Brotchie Jonathan M   +10 more
core   +1 more source

Sporadic Creutzfeldt-Jakob Disease.

, 2011
The book chapter describes the epidemiology, genetics, clinical features, imaging and laboratory findings, histopathology (including immunohistochemistry and ultrastructure), molecular pathology, subtype classification and differential diagnosis of ...
Head M. W., PARCHI, PIERO, Ironside J. W., Budka H., Gambetti P., Tagliavini F.   +5 more
core   +1 more source

Decontamination of prions, prion-associated amyloid and inefectivity from surgical stainless steel - implications for the risk of iatrogenic transmission of CJD

, 2009
The physicochemical nature of the infectious agent in prion diseases creates asignificant challenge for decontamination services. It has been shown to be both resistant tostandard methods of decontamination, used to inactivate viruses and bacteria, and ...
Howlin, Robert
core  

The presence of valine at residue 129 in human prion protein accelerates amyloid formation

, 2005
The polymorphism at residue 129 of the human PRNP gene modulates disease susceptibility and the clinicopathological phenotypes in human transmissible spongiform encephalopathies.
Tahiri-Alaoui, Abdessamad, Gill, A, Shaw, Michael, Shaw, M, Baskakov, I, Breydo, L, James, W, Tahiri-Alaoui, A, Disterer, Petra, Gill, Andrew, Baskakov, Ilia, Breydo, Leonid, Disterer, P, James, William   +13 more
core   +1 more source

Developments in variant Creutzfeldt Jakob disease

, 2000
The announcement on 17 July 2000 that the rate of increase in the incidence of variant Creutzfeldt Jakob disease (vCJD) in the United Kingdom (UK) had reached statistical significance makes the current issue of Eurosurveillance particularly timely.
O N Gill
core   +1 more source

Creutzfeldt-Jakob Disease: Guidelines for Social Workers in England [PDF]

, 2018
These guidelines are written for social workers and other social care professionals who work with people with Creutzfeldt-Jakob disease (CJD) and their families.
Mead, Simon, Simcock, Peter, Tesfamichael, Selam, Manthorpe, Jill   +3 more
core  

Age and Variant Creutzfeldt-Jakob Disease

, 2003
The young and stable median age of those who die of variant Creutzfeldt-Jakob disease has been attributed to age-dependent infection rates. This analysis shows that an influence of age on risk for death after infection better explains age patterns ...
Peter Bacchetti
core   +1 more source

Development of a sensitive cell culture system to assess prion infectivity and the efficacy of prion decontamination technologies

, 2012
Creutzfeldt-Jakob disease (CJD) can be iatrogenically transmitted during transplants, grafts and transfusions from CJD infected donors and also contaminated surgical instruments.
Secker, Thomas
core  

Degeneração cortico-estriato-medular: relato de um caso com achados clínicos e patológicos sugestivos de doença de Creutzfeldt-Jakob Cortico-striate-spinal degeneration: report of a case with clinical and pathological findings suggestive of Creutzfeldt-Jakob disease

Arquivos de Neuro-Psiquiatria, 1976
É apresentado caso sugestivo de doença de Creutzfeldt-Jakob em adulto jovem. O estudo anátomo-patológico revelou alteração difusa no córtice cerebral, núcleos da base e medula, constituídas por degeneração neuronal, gliose, espongiose e infiltração ...
Osvaldo J. M. Nascimento, Marcos R. G. de Freitas   +1 more
doaj  

Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease.

, 2004
Currently, definite peripheral markers for the in vivo diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) are not available. Here, we report the presence of pathological prion protein in the olfactory mucosa of a case with sporadic Creutzfeldt-Jakob ...
Colucci M., ZANUSSO, Gianluigi, MONACO, Salvatore, Tagliavini F., Cordone M. P., Tabaton M., Giaccone G.   +6 more
core   +1 more source