Results 31 to 40 of about 26,898 (212)

Application value of real ⁃ time quaking ⁃ induced conversion technology in clinical diagnosis of Creutzfeldt⁃Jakob disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Creutzfeldt⁃Jakob disease (CJD) is a group of clinically rare neurodegenerative diseases caused by misfolding of prion proteins, and is the most common type of human prion diseases.
Dian HE
doaj   +1 more source

Sporadic Creutzfeldt-Jakob Disease Presenting as Corticobasal Syndrome: A Rare Case

Türk Nöroloji Dergisi, 2018
Murat Gültekin, Recep Baydemir, Mehmet Fatih Göl, Meral Mirza   +3 more
doaj   +2 more sources

Sporadic MM-1 Type Creutzfeldt-Jakob Disease With Hemiballic Presentation and No Cognitive Impairment Until Death: How New NCJDRSU Diagnostic Criteria May Allow Early Diagnosis

Frontiers in Neurology, 2018
Sporadic Creutzfeldt-Jakob disease is the most common human prion disorder. Although associated with heterogeneous clinical phenotypes, its distinctive feature is the presence of a rapidly progressive multidomain cognitive impairment.
Lorenzo Saraceno, Vito A. G. Ricigliano, Michele Cavalli, Alessandro Cagol, Giovanna Bosco, Fabio Moda, Paola Caroppo, Giovanni Meola, Giovanni Meola   +8 more
doaj   +1 more source

Negative Diffusion Weighted Imaging on Magnetic Resonance Imaging of the Brain in Creutzfeldt–Jakob Disease

Case Reports in Neurological Medicine, 2020
A 76-year-old Caucasian woman initially presented to the Duke Memory Disorders clinic with a 9-month history of a rapid decline in cognitive, motor, and neuropsychiatric function.
Elijah Lackey, Deepal P. Shah-Zamora, Jodi Hawes, Andy J. Liu   +3 more
doaj   +1 more source

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Kretzschmar, H. A., Niedmann, P., Otto, M., Poser, S., Schmidt, H., Schroter, A.   +6 more
core   +1 more source

Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]

, 2006
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel, Diamond, Michael, Koerper, Marion A, Kulkarni, Roshni, Ludlam, Christopher A, Powderly, William G, Ritchie, Bruce, Siegel, Jamie, Simmonds, Peter, Stanley, Samuel, Tapper, Michael L, von Depka, Mario   +11 more
core   +5 more sources

Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins [PDF]

, 2011
Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant Creutzfeldt-Jakob diseases, Gerstmann-Str$\ddot{a}$ussler ...
Zhang, Jiapu
core   +2 more sources

Patients with Prion: Blocking Precautions Epidemiological

Revista de Epidemiologia e Controle de Infecção, 2017
Objective: To present the epidemiological blocking measures carried out in the hospital care of patients with Creutzfeldt-Jakob disease. Methodology: retrospective case series of four patients admitted to a referral hospital in southern Brazil, from June
Liarine Fernandes Bedin, Jaqueline Petittembert Fonseca, Ariane Baptista Monteiro, Luzia Fernandes Millão, Rita Catalina Aquino Caregnato   +4 more
doaj   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, Collinge, J, Lowe, J, Lukic, A, MacKay, A, Mead, S, Porter, MC, Rudge, P, Thompson, AG, Uphill, J   +9 more
core   +1 more source

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50. [PDF]

Eur J Neurol
This study investigated whether transmission ratio distortion (TRD) occurs in inherited prion diseases, specifically familial Creutzfeldt‐Jakob disease (p.E200K variant) and fatal familial insomnia (p.D178N variant), despite the theoretical 50% autosomal dominant inheritance risk.
Kortazar-Zubizarreta I, Manero-Azua A, Eraña H, Aguire U, Castilla J, Perez de Nanclares G.   +5 more
europepmc   +2 more sources