Results 41 to 50 of about 13,613 (255)

Creutzfeldt-Jakob disease after COVID-19: infection-induced prion protein misfolding? A case report

Prion, 2022
Creutzfeldt-Jakob disease (CJD) is a rare, fatal disease presenting with rapidly progressive neurological deficits caused by the accumulation of a misfolded form (PrPSc) of prion protein (PrPc).
Andrea Bernardini, Gian Luigi Gigli, Francesco Janes, Gaia Pellitteri, Chiara Ciardi, Martina Fabris, Mariarosaria Valente   +6 more
doaj   +1 more source

Pathologically confirmed autoimmune encephalitis in suspected Creutzfeldt-Jakob disease [PDF]

, 2015
Objective: To determine the clinical features and presence in CSF of antineuronal antibodies in patients with pathologically proven autoimmune encephalitis derived from a cohort of patients with suspected Creutzfeldt-Jakob disease (CJD).
Beukelaar, J.W.K. (Janet) de, Duijn, C.M. (Cornelia) van, Graaff, E. (Esther) de, Jansen, C. (Casper), Maat, P. (Peter), Rozemuller, A.J.M. (Annemieke), Schuur, M. (Maaike), Smitt, P.S., Titulaer, M.J. (Maarten), Van Coevorden, M.H. (Marleen H.)   +9 more
core   +1 more source

Treating seizures in Creutzfeldt–Jakob disease

Epilepsy and Behavior Case Reports, 2014
Seizures are known to occur in Creutzfeldt–Jakob disease (CJD). In the setting of a rapidly progressive condition with no effective therapy, determining appropriate treatment for seizures can be difficult if clinical morbidity is not obvious yet the ...
Marcus C. Ng, M. Brandon Westover, Andrew J. Cole   +2 more
doaj   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, Collinge, J, Lowe, J, Lukic, A, MacKay, A, Mead, S, Porter, MC, Rudge, P, Thompson, AG, Uphill, J   +9 more
core   +1 more source

Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP [PDF]

, 2009
Stop codon mutations in the gene encoding the prion protein (PRNP) are very rare and have thus far only been described in two patients with prion protein cerebral amyloid angiopathy (PrP-CAA).
Casper Jansen, Piero Parchi, Sabina Capellari, Ad J. Vermeij, Patrizia Corrado, Frank Baas, Rosaria Strammiello, Willem A. van Gool, John C. van Swieten, Annemieke J. M. Rozemuller, H Braak, V Campana, S Capellari, S Capellari, B Chesebro, U Finckh, P Gambetti, B Ghetti, B Ghetti, B Ghetti, B Ghetti, G Giaccone, F Gray, C Haass, J Hardy, SI Ikeda, JW Ironside, C Keohane, GR Mallucci, M Mohr, R Nitrini, S Notari, C Paquet, P Parchi, P Parchi, P Piccardo, T Revesz, F Tagliavini, J Tateishi, DR Thal, HV Vinters, S Vogelgesang, J Woulfe, M Yamada   +43 more
core   +8 more sources

The Changing Face of Paediatric Human Growth Hormone Therapy

Endocrines, 2022
Human growth hormone (hGH) has been used therapeutically to promote growth in children for over 60 years. Pituitary-extracted hGH has demonstrated positive growth promotion since the early 1960s.
Martin O. Savage
doaj   +1 more source

Proteínas 14-3-3 y tau positivas en un caso de enfermedad esporádica de Creutzfeldt-Jakob y una breve reseña de las enfermedades priónicas en Colombia

Biomédica: revista del Instituto Nacional de Salud, 2016
Las enfermedades priónicas son alteraciones neurodegenerativas raras que ocurren en todo el mundo y afectan tanto a humanos como a animales. En el presente artículo, se reporta un caso con diagnóstico confirmado de enfermedad esporádica de Creutzfeldt ...
Kevin Escandón-Vargas, Andrés Zorrilla-Vaca, Raúl Heli Corral-Prado   +2 more
doaj   +1 more source

The Importance of Rapid Consideration of Creutzfeldt- Jakob Disease in the Differential Diagnosis of Progressive Neurodegenerative Disease: A Case Report

International Journal of Medical Students, 2016
Background: Creutzfeldt-Jakob disease (CJD) is a prion disease characterized by misfolded proteins that lead to neurodegeneration and inevitable death. Classic sporadic CJD presents primarily with cognitive symptoms and ataxia without visual impairment ...
Arthur Joseph, Jacob Core, Daniel Solano, Marquand Patton, Shaun Smart   +4 more
doaj   +1 more source

Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias:a longitudinal multicentre study over 10 years [PDF]

, 2012
To date, cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of Creutzfeldt–Jakob disease cases.
Aguzzi, Adriano, Calero, Miguel, Gawinecka, Joanna, Green, Alison, Karch, Andre, Knight, Richard, Kulczycki, Jerzy, Ladogana, Anna, Laplanche, Jean-Louis, Mitrova, Eva, Peoc'h, Katell, Pocchiari, Maurizio, Saiz, Albert, Sanchez-Juan, Pascual, Sanchez-Valle, Raquel, Schelzke, Gabi, Sklaviadis, Theodor, Slivarichova, Dana, Stoeck, Katharina, van Duijn, Cornelia M., Zerr, Inga   +20 more
core   +1 more source

High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins: usefulness in laboratory diagnosis of human prion disease [PDF]

, 2011
Background The gamma-isoform of the 14-3-3 protein (14-3-3 gamma) is expressed in neurons, and could be a specific marker for neuronal damage.
Yuki Matsui, Katsuya Satoh, Toshiaki Miyazaki, Susumu Shirabe, Ryuichiro Atarashi, Kazuo Mutsukura, Akira Satoh, Yasufumi Kataoka, Noriyuki Nishida   +8 more
core   +1 more source