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Las enfermedades priónicas son alteraciones neurodegenerativas raras que ocurren en todo el mundo y afectan tanto a humanos como a animales. En el presente artículo, se reporta un caso con diagnóstico confirmado de enfermedad esporádica de Creutzfeldt ...
Kevin Escandón-Vargas +2 more
doaj +1 more source
An Atypical Presentation of Creutzfeldt-Jakob Disease With a Heidenhain Variant and Balint's Syndrome [PDF]
Creutzfeldt-Jakob disease (CJD) is known for a rapidly progressive decline in cognitive functions due to an underlying infection from a prion. This case involves a unique and atypical variant of CJD that was difficult to diagnose for the investigating medical teams.
Gupta, Abhishek, Dhingra, Anurag
openaire +2 more sources
Background: Creutzfeldt-Jakob disease (CJD) is a prion disease characterized by misfolded proteins that lead to neurodegeneration and inevitable death. Classic sporadic CJD presents primarily with cognitive symptoms and ataxia without visual impairment ...
Arthur Joseph +4 more
doaj +1 more source
Functional Magnetic Resonance Imaging in the Final Stage of Creutzfeldt-Jakob Disease
Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare fatal degenerative disease of the central nervous system. The clinical course is characterized by rapid progression of neurological and neuromuscular symptoms.
Stefan M. Golaszewski +11 more
doaj +1 more source
Creutzfeldt-Jakob disease and sleep disorders
Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease caused by prion protein infection. Compared with other neurodegenerative diseases, neuronal cell apoptosis in CJD occurs more rapidly.
Jian-nan ZHU +5 more
doaj +1 more source
A Creutzfeldt-Jakob like syndrome due to lithium toxicity. [PDF]
Two patients with lithium toxicity presented with a neurological syndrome suggesting a diagnosis of Creutzfeldt-Jakob disease. In both cases, the initial EEG was consistent with this diagnosis. Neither patient had permanent neurological sequelae and the EEG returned to normal.
S J, Smith, R S, Kocen
openaire +2 more sources
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
MicroRNAs in Prion Diseases—From Molecular Mechanisms to Insights in Translational Medicine
MicroRNAs (miRNAs) are small non-coding RNA molecules able to post-transcriptionally regulate gene expression via base-pairing with partially complementary sequences of target transcripts.
Danyel Fernandes Contiliani +3 more
doaj +1 more source

