Results 91 to 100 of about 24,776 (211)

CHO Cell Line Selection through Multi‐Criteria Analysis Reveals Critical Impact of Gas Overlay

Biotechnology Journal, Volume 21, Issue 3, March 2026.
Graphical Abstract and Lay Summary Multivariate data analysis (MVDA) integrated productivity, growth, stability, and metabolism to rank monoclonal antibody producing CHO clones. From 24 candidates cultivated in well plates, eight were selected for bioreactor experiments. Bioreactor cultures without air overlay had increased pCO2 and unexpectedly better
Jimmy Gaudreault, Petko Komsalov, Jason Kuipers, Lucas Lemire, Brian Cass, Linda Lamoureux, Julien Leroy, Christopher Corbeil, Traian Sulea, Robert Voyer, Simon Joubert, Yves Durocher, Olivier Henry, Phuong Lan Pham   +13 more
wiley   +1 more source

First person – De-Li Xu

Biology Open, 2018
First person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. De-Li Xu is first author on ‘Seasonal variations in cellular and
doaj   +1 more source

The mentolabial approach is a novel, safe, and effective method of blood collection in rats (Rattus norvegicus) and Chinese hamsters (Cricetulus griseus).

Journal of the American Veterinary Medical Association
Objective To assess the safety, efficacy, and repeatability of a novel technique, mentolabial blood collection, in rats (Rattus norvegicus), Chinese hamsters (Cricetulus griseus), and long-tailed chinchillas (Chinchilla lanigera) and to characterize the ...
Haley Johnson, J. Luapan, Melissa Seiberlich, Cory Brayton, Isabel A. Jimenez   +4 more
semanticscholar   +1 more source

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, Volume 42, Issue 2, March/April 2026.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, Volume 46, Issue 3, Page 950-960, March 2026.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

DIET COMPOSITION OF THE WINTERING Asio otus L. (STRIGIFORMES: STRIGIDAE) IN TWO DIFFERENT HABITAT TYPES IN TURKEY

Trakya University Journal of Natural Sciences, 2021
In this study, we analysed a total of 691 pellets of the Long-eared Owl (Asio otus L.) collected from Edirne (Suburban), İstanbul (Suburban) and Kars (High altitude steppe) provinces in January-February 2019.
Ahmet Yesari Selçuk, Ömral Ünsal Özkoç, Melisa Bal, Umut Güngör, Osman Özmen Yeltekin   +4 more
doaj   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan, Christiana‐Kondylo Sideri, Michael Henry, Selvaprakash Karuppuchamy, Esen Efeoglu, Paula Meleady   +5 more
wiley   +1 more source

Cricetulus alticola Thomas 1917

, 2005
Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1041, DOI: 10.5281/zenodo ...
Wilson, Don E., Reeder, DeeAnn
openaire   +2 more sources

Computational Approaches for Pathway‐Centric Analysis of Protein Post‐Translational Modifications

PROTEOMICS, Volume 25, Issue 21-22, Page 41-61, November 2025.
ABSTRACT Protein function is dynamically modulated by post‐translational modifications (PTMs). Many different types of PTMs can nowadays be identified and quantified at a large scale using mass spectrometry. It is well known that many PTMs have an effect on protein function and cellular processes, and they should be studied not in isolation, but in the
Julian Müller, Bernhard Kuster, Matthew The   +2 more
wiley   +1 more source

First genotoxicity study of Paraná river water from Argentina using cells from the clam Corbicula fluminea (Veneroida Corbiculidae) and Chinese hamster (Cricetulus griseus Rodentia, Cricetidae) K1 cells in the comet assay

Genetics and Molecular Biology, 2008
High concentrations of xenobiotics from urban and industrial wastes have contributed to the contamination of many aquatic environments. We used the comet assay to evaluate the genotoxic potential of water collected from the River Paraná, which receives a
Jacqueline D. Caffetti, Mário S. Mantovani, María C. Pastori, Alberto S. Fenocchio   +3 more
doaj   +1 more source