Results 81 to 90 of about 23,196 (196)

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

Biotechnology and Bioengineering, Volume 122, Issue 7, Page 1898-1913, July 2025.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson, Joanne Watson, Susan Rosser, Ellie Hawke, Andrew Pitt, Tessa Moses, Leon Pybus, Magnus Rattray, Alan J. Dickson, Jean‐Marc Schwartz   +9 more
wiley   +1 more source

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. [PDF]

, 2013
Chinese hamster ovary (CHO) cells, first isolated in 1957, are the preferred production host for many therapeutic proteins. Although genetic heterogeneity among CHO cell lines has been well documented, a systematic, nucleotide-resolution characterization
Bian, Chao, Rosenbloom, Jeffrey, Nagarajan, Harish, Xu, Xun, George Yerganian, Deniz Baycin-Hizal, Bordbar, Aarash, Min Xie, Yerganian, George, Chao Bian, Betenbaugh, Michael, Chen, Wenbin, Förster, Jochen, Anne M Roth, Latif, Haythem, Harish Nagarajan, O'Brien, Edward, Aarash Bordbar, Yuxiang Li, Xie, Min, Baycin-Hizal, Deniz, Famili, Iman, Jeffrey Rosenbloom, Li, Ning, Xun Xu, Jochen Forster, Michael J Betenbaugh, Palsson, Bernhard O, Lewis, Nathan E., Nathan E Lewis, Wang, Jun, Lewis, Nathan E, Jun Wang, Edward O'Brien, Iman Famili, Bernhard O Palsson, Wenbin Chen, Haythem Latif, Li, Yuxiang, Ning Li, Roth, Anne M, Xin Liu, Liu, Xin, Roth, Anne M., Palsson, Bernhard O.   +44 more
core   +1 more source

cba‐miR‐222‐3p involved in photoperiod‐induced apoptosis in testes of striped hamsters by targeting TRAF7

Integrative Zoology, Volume 20, Issue 4, Page 836-849, July 2025.
The cba‐miR‐222‐3p affects the MAPK signaling pathway by targeting TRAF7, thereby participating in the induction of apoptosis in the testes of striped hamsters under different photoperiods. Abstract The role of miRNAs in the regulation of seasonal reproduction in rodents, particularly in relation to photoperiod changes, is still poorly understood ...
Shuo WANG, Jinhui XU, Xingchen WANG, Mingdi WANG, Huiliang XUE, Ming WU, Chao FAN, Lei CHEN, Laixiang XU   +8 more
wiley   +1 more source

"Investigation on Zoonotic Cutaneous Leishm- aniasis, Southern Iran " [PDF]

Iranian Journal of Public Health, 2004
Since occurrence of an epidemic of cutaneous leishmaniasis with high incidence of disease (8.9/1000) in Arsanjan county, Fars province, southern Iran, an attempt was made to investigate an epidemiological study during 2001-2002. Symptomatic investigation
Y Rassi, E Javadian, M Jalali, MH Motazedian, H Vatndoost   +4 more
doaj   +1 more source

Sequencing and analysis of the complete mitochondrial genome of the northern red-backed vole (Myodes rutilus) from China

Mitochondrial DNA. Part B. Resources, 2019
The complete mitogenome sequence of the northern red-backed vole (Myodes rutilus) was determined using long polymerase chain reaction (PCR). The genome was 16,296 bp in length and contained 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA ...
Jin Zhi-Min, Yu Cheng-Wen, Liu Zhu
doaj   +1 more source

Development of a single‐nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters

Animal Models and Experimental Medicine, Volume 8, Issue 5, Page 916-921, May 2025.
Here, we developed a novel Chinese hamster genetic quality detection system using single‐nucleotide polymorphism (SNP) markers following this process. To obtain SNP loci, we conducted whole genome sequencing on 24 Chinese hamsters. Then, we employed an SNP loci screening criterion that we set up previously and initially screened 214 SNP loci with wide ...
Minghe Sun, Yafang Guo, Zhengnan Ren, Ang Song, Jing Lu, Changlong Li, Jianyi Lv, Meng Guo, Xin Liu, Xiaoyan Du, Zhaoyang Chen, Guohua Song, Yan He, Zhenwen Chen, Xueyun Huo   +14 more
wiley   +1 more source

Cricetulus Milne-Edwards 1867

, 2005
Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1041, DOI: 10.5281/zenodo ...
Wilson, Don E., Reeder, DeeAnn
openaire   +2 more sources

Evolution of the Neopsylla hongyangensis Mitogenome: Insights Into the Mitogenomic Evolution of the Orders Siphonaptera and the Phthiraptera

Ecology and Evolution, Volume 15, Issue 3, March 2025.
The Neopsylla hongyangensis is an important medical insect that transmits plague. We sequenced the mitogenome of N. hongyangensis and constructed a phylogenetic tree for the order Siphonaptera. In addition, we explored the mitogenomic evolution of the orders Siphonaptera and Phthiraptera, which both belong to the class Insects, on warm‐blooded animals ...
Xiaoxia Lin, Ju Pu, Wenge Dong
wiley   +1 more source

Distribution and Host Selection of the Chigger Mite Leptotrombidium rupestre, a Potential Vector of Scrub Typhus, in Southwest China

Veterinary Medicine and Science, Volume 11, Issue 2, March 2025.
Based on field surveys in southwest China between 2001 and 2022, this paper retrospectively reports the distribution and host selection of L. rupestre in the region for the first time. A total of 4675 L. rupestre were identified from 28 species of small mammal hosts in 23 of 114 survey sites and it was mainly distributed in higher latitudes (31–33° N ...
Rong Yu, Xian‐Guo Guo, Yan Lv, Peng‐Wu Yin, Wen‐Yu Song, Pei‐Ying Peng, Ti‐Jun Qian, Rong Xiang, Yan‐Ling Chen, Bei Li   +9 more
wiley   +1 more source

A PRELIMINARY REPORT OF BABESIA MICROTI IN RODENTS

Iranian Journal of Public Health, 1997
Altogether, 132 rodents of 4 species of Meriones persicus , Cricetulus migratorius, Mus muscri~ius and Allactaga dater were collected with live traps from different parts of Meshkin - shahr district from summer 1373 to autumn 1374.
M. Mohebali
doaj