Results 91 to 100 of about 13,422 (244)

Unique Strain of Crimean–Congo Hemorrhagic Fever Virus, Mali

Emerging Infectious Diseases, 2014
To the Editor: Crimean-Congo hemorrhagic fever (CCHF) is an acute viral infection that causes mild to severe hemorrhagic fever characterized by petechiae, ecchymosis, disseminated intravascular coagulation, and multi-organ failure (1). The etiologic agent, CCHF virus (CCHFV; family Bunyaviridae, genus Nairovirus), is maintained in enzootic cycles ...
Marko Zivcec, Ousmane Maïga, Ashley Kelly, Friederike Feldmann, Nafomon Sogoba, Tom G. Schwan, Heinz Feldmann, David Safronetz   +7 more
openaire   +3 more sources

Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions

Frontiers in Cellular and Infection Microbiology, 2023
Crimean-Congo hemorrhagic fever virus (CCHFV; family Nairoviridae) is a tick-borne pathogen that frequently causes lethal disease in humans. CCHFV has a wide geographic distribution, and cases have been reported in Africa, Asia, the Middle East, and ...
F. Scholte, E. Karaaslan, T. Neal, T. Sorvillo, S. Genzer, S. R. Welch, J. Coleman-McCray, J. Spengler, M. Kainulainen, J. Montgomery, S. Pegan, É. Bergeron, C. Spiropoulou, Takaaki Koma, Vero ´ nica Mart ı ´ n Garc ı ´ a, Scholte Fem, O. ’. Karaaslan E, T. Neal, T. Sorvillo, Scott Genzer, Welch, Spengler, MH Kainulainen, J. Montgomery, S. Pegan, CF Spiropoulou, Welch Genzer, Bergeron Spiropoulou. This Pegan   +27 more
semanticscholar   +1 more source

Prognostic Value of Admission Glucose and Extended Lipid Profile in Patients with Crimean‐Congo Hemorrhagic Fever

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Crimean‐Congo hemorrhagic fever (CCHF) is a life‐threatening viral hemorrhagic fever with a highly variable clinical course. While viral and inflammatory markers determining disease severity are well defined, the impact of the host's metabolic status on CCHF severity remains largely unexplored.
Yasemin Çakır Kıymaz, Cihad Baysal, Caner Öksüz, Seyit Ali Büyüktuna, Nazif Elaldı   +4 more
wiley   +1 more source

Crimean-Congo Hemorrhagic Fever Virus Genome in Tick from Migratory Bird, Italy

Emerging Infectious Diseases, 2019
We detected Crimean-Congo hemorrhagic fever virus in a Hyalomma rufipes nymph collected from a whinchat (Saxicola rubetra) on the island of Ventotene in April 2017. Partial genome sequences suggest the virus originated in Africa.
Elisa Mancuso, Luciano Toma, Andrea Polci, Silvio G. d’Alessio, Marco Di Luca, Massimiliano Orsini, Marco Di Domenico, Maurilia Marcacci, Giuseppe Mancini, Fernando Spina, Maria Goffredo, Federica Monaco   +11 more
doaj   +1 more source

HMGB1 Is a Potential Biomarker for Severe Viral Hemorrhagic Fevers. [PDF]

PLoS Neglected Tropical Diseases, 2016
Hemorrhagic fever with renal syndrome (HFRS) and Crimean-Congo hemorrhagic fever (CCHF) are common representatives of viral hemorrhagic fevers still often neglected in some parts of the world.
Katarina Resman Rus, Luka Fajs, Miša Korva, Tatjana Avšič-Županc   +3 more
doaj   +1 more source

Crimean-congo hemorrhagic fever: Case series from a medical center in golestan province, Northeast of Iran (2004-2006) [PDF]

, 2006
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed lethal disease, worldwide. Humans are usually infected with CCHF virus through a tick bite or close contact with viral contaminated tissues or with blood of domestic animals or of infected ...
Abbasi, A., Besharat, S., Jabbari, A., Kalavi, K., Moradi, A.   +4 more
core  

A TLR8 Variant Identified From Whole Exome Sequencing as a Sepsis‐Prone Mutation

FASEB BioAdvances, Volume 8, Issue 4, April 2026.
Whole‐exome sequencing of sepsis patients identified a recurrent high‐impact TLR8 rs3764880 variant enriched in bacterial sepsis. Single‐cell transcriptomics localized elevated TLR8 expression to non‐classical monocytes, while bulk RNA‐seq and functional assays demonstrated enhanced IFN‐β responses following TLR8 stimulation.
Fahd Alhamdan, Stefano Gianoli, Xioahui Han, Sophia Koutsogiannaki   +3 more
wiley   +1 more source

Crimean-Congo Hemorrhagic Fever Virus in Humans and Livestock, Pakistan, 2015–2017

Emerging Infectious Diseases, 2020
We detected Crimean-Congo hemorrhagic fever virus infections in 4 provinces of Pakistan during 2017–2018. Overall, seroprevalence was 2.7% in humans and 36.2% in domestic livestock.
Ali Zohaib, Muhammad Saqib, Muhammad A. Athar, Muhammad H. Hussain, Awais-ur-Rahman Sial, Muhammad H. Tayyab, Murrafa Batool, Halima Sadia, Zeeshan Taj, Usman Tahir, Muhammad Y. Jakhrani, Jawad Tayyab, Muhammad A. Kakar, Muhammad F. Shahid, Tahir Yaqub, Jingyuan Zhang, Qiaoli Wu, Fei Deng, Victor M. Corman, Shu Shen, Iahtasham Khan, Zheng-Li Shi   +21 more
doaj   +1 more source

An outbreak of West Nile fever among migrants in Kisangani, Democratic Republic of Congo. [PDF]

, 1999
In February 1998, an outbreak of acute febrile illness was reported from the Kapalata military camp in Kisangani, the Democratic Republic of Congo. The illness was characterized by an acute onset of fever associated with severe headache, arthralgia ...
Copra, C. (Cederick), Groen, J. (Jan), Heuvelmans, H., Nur, Y.A., Osterhaus, A.D.M.E. (Albert), Tuynman, W.   +5 more
core   +4 more sources

A DNA-based vaccine protects against Crimean-Congo hemorrhagic fever virus disease in a Cynomolgus macaque model

Nature Microbiology, 2020
There is currently no specific prophylaxis or vaccine against Crimean-Congo haemorrhagic fever virus (CCHFV). Crimean-Congo haemorrhagic fever (CCHF) is a severe febrile illness transmitted by Hyalomma ticks in endemic areas, handling of infected ...
David W. Hawman, G. Ahlén, K. S. Appelberg, Kimberly Meade-White, P. Hanley, D. Scott, V. Monteil, S. Devignot, A. Okumura, F. Weber, H. Feldmann, M. Sällberg, A. Mirazimi, A. Mirazimi, A. Mirazimi   +14 more
semanticscholar   +1 more source