Results 171 to 180 of about 5,358,439 (388)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

The Agricultural Crisis [PDF]

, 1898
Giuseppe M. Fiamingo
openalex   +1 more source

Protecting Organization Reputations During a Crisis: The Development and Application of Situational Crisis Communication Theory

, 2007
W. Coombs
semanticscholar   +1 more source

Masters of disasters? Challenges and opportunities for SMEs in times of crisis

Journal of business research, 2020
Fabian Eggers
semanticscholar   +1 more source

Trade crisis - what trade crisis? [PDF]

Giordano Mion and colleagues investigate whether the trade collapse of 2008-09 reflected a crisis of international trade ...
Giordano Mion
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The Moral Crisis within the Church [PDF]

, 1908
Frank Ilsley Paradise
openalex   +1 more source

¿Crisis, qué crisis?

revista PH, 2013
"...Por tanto, mi axioma será justamente ese, que el patrimonio “se dice” (como el “ser” aristotélico) de muchas maneras, una de ellas es la económica.  ¿Es esta faceta económica la más relevante? Esta es la cuestión, maximizada por los tiempos que corren. Pero, en mi opinión, tal emergencia histórica carece de sentido.
openaire   +3 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Book Review: VI. Miscellaneous: Christianity and the Social Crisis [PDF]

, 1907
J. L. Kesler
openalex   +1 more source