Results 61 to 70 of about 5,933,514 (305)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Crisis pregnancy and pregnancy decision making: An outline of influencing factors [PDF]
This document aims to review research literature in order to: • outline and describe the factors that have been demonstrated to affect the level and incidence of crisis pregnancy • examine the factors that affect a woman’s decision when faced with a ...
O’Keeffe, Stephanie
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The communication of messages of the impending impact of some natural disaster agent can play a key role in averting natural catastrophe. This article examines the social processes involved in disaster warnings which function to elicit evacuation in such threat situations.
Dennis S. Mileti, E.M. Beck
openaire +1 more source
This paper compares two design thinking workshops conducted at the International Crisis and Risk Communication Conferences (ICRCC) in 2024 and 2025, each tackling a distinct yet equally wicked communication challenge.
Vogel, Béatrice +6 more
core +1 more source
Secondary Crisis Communication. A question of Actual or perceived credibility? [PDF]
An important aspect of crisis communication is secondary crisis communication, which focuses on how people communicate during a crisis. This study seeks to explore the mechanism of credibility in secondary crisis communication.
Johansson, Bengt, Johansson, Bengt,
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
While social media enhance diverse aspects of crisis information sharing and engagement, its distinctiveness lies in the wide range of visuals that can be shared and linked to text-based messages.
Carmen Daniela Maier +3 more
core +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source

