Results 101 to 110 of about 122,969 (260)

Evaluation of Ongoing Crisis Intervention Team (CIT) Training for Law Enforcement Using the ECHO Model. [PDF]

J Police Crim Psychol, 2022
Crisanti AS, Fairfax-Columbo J, Duran D, Rosenbaum NA, Melendrez B, Trujillo I, Earheart JA, Tinney M.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Crisis Intervention Team (CIT) training and impact on mental illness and substance use-related stigma among law enforcement. [PDF]

Drug Alcohol Depend Rep, 2022
Nick GA, Williams S, Lekas HM, Pahl K, Blau C, Kamin D, Fuller-Lewis C.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cooperation of the School With the Family and the Local Community – Selected Aspects

Horyzonty Wychowania
RESEARCH OBJECTIVE: The article describes the conditions, assumptions and benefits regarding the process of cooperation of the school with the family and the local community in the context of selected educational aspects.
Anna Błasiak, Sylwia Michalec-Jękot
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Risk Assessment and Crisis Intervention for Youth in a Time of Telehealth. [PDF]

Contemp Sch Psychol, 2021
Holland M, Hawks J, Morelli LC, Khan Z.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Longitudinal associations between peer rejection, fear of negative evaluation and depressive symptoms in Chinese adolescents: a cross-lagged panel analysis

BMC Psychology
Background While peer rejection and depressive symptoms are robustly linked in adolescents, their directional relationships and underlying mechanisms remain unclear, especially in Chinese cultural contexts and mid- to late adolescence.
Yuelin Chen, Zihan Xie, Ying Yang
doaj   +1 more source

A Suicide Monitoring and Crisis Intervention Strategy Based on Knowledge Graph Technology for "Tree Hole" Microblog Users in China. [PDF]

Front Psychol, 2021
Yang BX, Xia L, Liu L, Nie W, Liu Q, Li XY, Ao MQ, Wang XQ, Xie YD, Liu Z, Huang YJ, Huang Z, Gong X, Luo D.   +13 more
europepmc   +1 more source