Results 81 to 90 of about 122,969 (260)

Remote crisis intervention and suicide risk management in COVID-19 frontline healthcare workers. [PDF]

Front Psychol, 2023
Robles R, Infante S, Feria M, Arango I, Tirado E, Rodríguez-Delgado A, Miranda E, Fresán A, Becerra C, Escamilla R, Madrigal de León EA.   +10 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Negative emotion alignment: The assimilation effect of facial emotion perception in a negative emotional crowd

i-Perception
Emotion perception of the target face within an emotional crowd is influenced by the intensity of surrounding emotional faces. The present study investigated whether participants perceived the target face's emotional intensity as more aligned with the ...
Jiaotao Cai, Yanmei Wang
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Thinking versus doing: how congruency between cognitive and actional future orientation affects left-behind children’s life satisfaction

BMC Psychology
Background Millions of children are left behind in rural areas of China while their parents work in urban areas, placing them at heightened risk for poor mental health outcomes.
Tong Zhao, Shuang Li, Ying Yang, Mohan Wang, Lijuan Cui   +4 more
doaj   +1 more source

Revisiting Research Safety Protocols: The Urgency for Alternatives to Law Enforcement in Crisis Intervention. [PDF]

Psychiatr Serv, 2023
Anene E, Nallajerla M, Bath EPJ, Castillo EG.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Network modeling of problematic social media use components in college student social media users

Frontiers in Psychiatry
BackgroundWhile the constitutive features of problematic social media use (PSMU) have been formulated, there has been a lack of studies in the field examining the structure of relationships among PSMU components.MethodThis study employed network analytic
Jianyong Chen, Jianyong Chen, Ting Su, Ting Su, Junqiang Dong, Yuzhi Li, Yuzhi Li, Ju Feng, Ju Feng, Yingxiu Chen, Yingxiu Chen, Gu Liu, Gu Liu   +12 more
doaj   +1 more source