Results 81 to 90 of about 3,275,688 (215)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Efficiency Recalibrates Social‐Emotional Trade‐Offs Behind Partner Choice in Direct Reciprocity through Intention‐Specific Neural Bases

open access: yesAdvanced Science
Direct reciprocity, in which beneficiaries return favors to benefactors, is a cornerstone of human cooperation. Previous empirical work addresses partner control—how individuals decide whether and how much to reciprocate—whereas the equally critical ...
Rui Liao   +5 more
doaj   +1 more source

Scarcity and Cooperation: The Modulation of Social Norms

open access: yesBehavioral Sciences
Given the continued relevance of perceived scarcity, understanding how a scarcity mindset influences human cooperation remains critical. However, previous research has yielded mixed results regarding this relationship.
Qiuling Luo   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

School crisis Prevention & Intervention

open access: yes, 2019
In the latest edition of School Crisis Prevention & Intervention, Mary Margaret Kerr, a nationally recognized expert in school crisis response and a leading urban educator, along with new coauthor, Garry King, a specialist in youth welfare, synthesizes ...
King, Garry, Kerr, Mary Margaret
core  

A naturalistic study of the effectiveness of a four-session format: the brief psychodynamic intervention

open access: yes, 2005
This study examined the effectiveness of the Brief Psychodynamic Intervention (BPI). The BPI is a 4-session intervention aiming at (a) developing an optimal plan to resolve the patient's crisis situation through the use of an initial dynamic ...
Drapeau, Martin   +2 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Can Perceivers Differentiate Intense Facial Expressions? Eye Movement Patterns

open access: yesBehavioral Sciences
Recent research on intense real-life faces has shown that although there was an objective difference in facial activities between intense winning faces and losing faces, viewers failed to differentiate the valence of such expressions.
Leyu Huang   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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