Results 61 to 70 of about 119,569 (285)

The acquired dyad inclination and decreased interpersonal brain communication in the pursuit of collective benefit

NeuroImage
People perform better collectively than individually, a phenomenon known as the collective benefit. To pursue the benefit, they may learn from previous behaviors, come to know whose initial opinion should be valued, and develop the inclination to take it
Shuyi Li, Linwei Yu, Xiaorong Gan, Yingying Hou, Yafeng Pan, Yi Luo, Yi Hu   +6 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Efficiency Recalibrates Social‐Emotional Trade‐Offs Behind Partner Choice in Direct Reciprocity through Intention‐Specific Neural Bases

Advanced Science
Direct reciprocity, in which beneficiaries return favors to benefactors, is a cornerstone of human cooperation. Previous empirical work addresses partner control—how individuals decide whether and how much to reciprocate—whereas the equally critical ...
Rui Liao, Xintong Li, Xuqi Liu, Yu Nan, Xiaolin Zhou, Xiaoxue Gao   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Scarcity and Cooperation: The Modulation of Social Norms

Behavioral Sciences
Given the continued relevance of perceived scarcity, understanding how a scarcity mindset influences human cooperation remains critical. However, previous research has yielded mixed results regarding this relationship.
Qiuling Luo, Changjin Qiu, Sihan Dong, Ronghui Tang, Chunhua Kang   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Can Perceivers Differentiate Intense Facial Expressions? Eye Movement Patterns

Behavioral Sciences
Recent research on intense real-life faces has shown that although there was an objective difference in facial activities between intense winning faces and losing faces, viewers failed to differentiate the valence of such expressions.
Leyu Huang, Tongtong Zhu, Jiaotao Cai, Yan Sun, Yanmei Wang   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source