Results 151 to 160 of about 207,049 (372)
Advanced Functional Materials, EarlyView.This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system
Nature, 2019 Bacteria use adaptive immune systems encoded by CRISPR and Cas genes to maintain genomic integrity when challenged by pathogens and mobile genetic elements1–3. Type I CRISPR–Cas systems typically target foreign DNA for degradation via joint action of the
T. Halpin-Healy +3 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
CRISPR- cas system in the acquisition of virulence genes in dental-root canal and hospital-acquired isolates of Enterococcus faecalis [PDF]
, 2020 Pourya Gholizadeh +8 more
openalex +1 more source
Discovery of Diverse CRISPR-Cas Systems and Expansion of the Genome Engineering Toolbox [PDF]
, 2023 Eugene V. Koonin +2 more
openalex +1 more source
, 2016 Bacteria can receive genetic material from other bacteria or invading bacteriophages primarily through horizontal gene transfer. These genetic exchanges can result in genome rearrangement and the acquisition of novel traits that assist cells with stresses and adverse environmental conditions.
Hakim, Joseph A. +4 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel +6 more
wiley +1 more source
Acta Biomedica Scientifica, 2018 Background. CRISPR/Cas systems loci are one of the functionally important patterns in bacterial genome which perform the role of “adaptive immune defense” from foreign nucleic acids.
N. A. Arefyeva +13 more
doaj +1 more source
CRISPR-Cas systems in Fusobacterium : An untapped genetic frontier [PDF]
, 2022 Ariana Umaña, Daniel J. Slade
openalex +1 more source
Annotation and Classification of CRISPR-Cas Systems [PDF]
, 2015 The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-associated proteins) is a prokaryotic adaptive immune system that is represented in most archaea and many bacteria. Among the currently known prokaryotic defense systems, the CRISPR-Cas genomic loci show unprecedented complexity and diversity.
Kira S, Makarova, Eugene V, Koonin
openaire +2 more sources