Results 211 to 220 of about 58,663 (324)

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Identification and characterization of two CRISPR/Cas systems associated with the mosquito microbiome. [PDF]

Access Microbiol, 2023
Hegde S, Rauch HE, Hughes GL, Shariat N.
europepmc   +2 more sources

High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

, 2014
Ryan E. Cobb, Yajie Wang, Huimin Zhao
openalex   +1 more source

Mathematical modelling of CRISPR-Cas system effects on biofilm formation [PDF]

, 2017
Qasim Ali, Lindi M. Wahl
openalex   +1 more source

Comparison of Structural Features of CRISPR-Cas Systems in Thermophilic Bacteria. [PDF]

Microorganisms, 2023
Wang C, Yang Y, Tang S, Liu Y, Wei Y, Wan X, Liu Y, Zhang Z, Sunkang Y.   +8 more
europepmc   +1 more source

Catalytic Hairpin Assembly‐Propelled Weak‐Inputs‐Strong‐Outputs (CP‐WISO) DNA Logic Nanodevices with Orthogonal Design and Contrary Logic Responses

Advanced Science, EarlyView.
Catalytic hairpin assembly‐propelled weak‐inputs‐strong‐outputs (CP‐WISO) DNA logic nanodevices with orthogonal design and contrary logic responses are innovatively fabricated. Moreover, the even and odd parity generators/checkers for ensuring normal molecular data transmission, and the logic‐programmed miRNA biosensors with ratiometric fluorescent ...
Xujuan Lv, Jiawen Han, Juan Wang, Zhihua Lv, Baojian Huang, Shuai Qin, Xuxin Yan, Shaojun Dong, Daoqing Fan   +8 more
wiley   +1 more source

Efficient generation of genome-modified mice via offset-nicking by CRISPR/Cas system

, 2014
Wataru Fujii, Asuka Onuma, Koji Sugiura, Kunihiko Naito   +3 more
openalex   +1 more source

Type III CRISPR-Cas systems generate cyclic oligoadenylate second messengers to activate Csm6 RNases [PDF]

, 2017
Ole Niewoehner, Carmela Garcia‐Doval, Jakob T. Rostøl, Christian Berk, Frank Schwede, Laurent Bigler, Jonathan Hall, Luciano A. Marraffini, Martin Jínek   +8 more
openalex   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Structure and Function of CRISPR-Cas System

, 2014
Akeo Shinkai
openalex   +2 more sources