Results 241 to 250 of about 64,886 (293)

Characteristics and immune functions of the endogenous CRISPR-Cas systems in myxobacteria. [PDF]

mSystems
Hu W-f, Yang J-y, Wang J-j, Yuan S-f, Yue X-j, Zhang Z, Zhang Y-q, Meng J-y, Li Y-z.   +8 more
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

CRISPR-Cas Systems Associated with Electrolyte-Gated Graphene-Based Transistors: How They Work and How to Combine Them. [PDF]

Biosensors (Basel)
Guermonprez P, Nioche P, Renaud L, Battaglini N, Sanaur S, Krejci E, Piro B.   +6 more
europepmc   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems. [PDF]

Nucleic Acids Res
Chen J, Lin X, Xiang W, Chen Y, Zhao Y, Huang L, Liu L.   +6 more
europepmc   +1 more source

Role of CRISPR-Cas systems and anti-CRISPR proteins in bacterial antibiotic resistance. [PDF]

Heliyon
Kadkhoda H, Gholizadeh P, Samadi Kafil H, Ghotaslou R, Pirzadeh T, Ahangarzadeh Rezaee M, Nabizadeh E, Feizi H, Aghazadeh M.   +8 more
europepmc   +1 more source

Repurposing endogenous type I-E CRISPR-Cas systems for natural product discovery in Streptomyces. [PDF]

Nat Commun
Zhou Q, Zhao Y, Ke C, Wang H, Gao S, Li H, Zhang Y, Ye Y, Luo Y.   +8 more
europepmc   +1 more source

Advances in plant pathogen detection: integrating recombinase polymerase amplification with CRISPR/Cas systems. [PDF]

3 Biotech
Anbazhagan P, Parameswari B, Anitha K, Chaitra GV, Bajaru B, Rajashree A, Mangrauthia SK, Yousuf F, Chalam VC, Singh GP.   +9 more
europepmc   +1 more source

Dual Detection of Hepatitis B and C Viruses Using CRISPR-Cas Systems and Lateral Flow Assay. [PDF]

J Nucleic Acids
Shahni SN, Albogami S, Azmi I, Pattnaik B, Chaudhuri R, Dev K, Iqbal J, Sharma A, Ahmad T.   +8 more
europepmc   +1 more source

Correction to 'DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems'. [PDF]

Nucleic Acids Res
europepmc   +1 more source