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CRISPR-Cas systems in prokaryotes [PDF]
Polish Journal of Microbiology, 2015 Prokaryotic organisms possess numerous strategies that enable survival in hostile conditions. Among others, these conditions include the invasion of foreign nucleic acids such as bacteriophages and plasmids.
Burmistrz, Michał, Pyrć, Krzysztof
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Insight into the natural regulatory mechanisms and clinical applications of the CRISPR-Cas system [PDF]
HeliyonCRISPR-Cas, the adaptive immune system exclusive to prokaryotes, confers resistance against foreign mobile genetic elements. The CRISPR-Cas system is now being exploited by scientists in a diverse range of genome editing applications.
Hui Cheng +7 more
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Frontiers in Microbiology, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR) and their CRISPR-associated proteins (Cas) are an adaptive immune system involved in specific defenses against the invasion of foreign mobile genetic elements, such as plasmids and phages.
Shuan Tao +9 more
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Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases
Diagnostics, 2022 The CRISPR/Cas system is a protective adaptive immune system against attacks from foreign mobile genetic elements. Since the discovery of the excellent target-specific sequence recognition ability of the CRISPR/Cas system, the CRISPR/Cas system has shown
Junwei Li +8 more
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Microbiology Spectrum, 2023 CRISPR-Cas is an adaptive immune system that allows bacteria to inactivate mobile genetic elements. Approximately 50% of bacteria harbor CRISPR-Cas; however, in the human pathogen Staphylococcus aureus, CRISPR-Cas loci are less common and often studied ...
Kasper Mikkelsen +11 more
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Microbiology Spectrum, 2022 Acinetobacter baumannii is a well-known human opportunistic pathogen in nosocomial infections, and the emergence of multidrug-resistant Acinetobacter baumannii has become a complex problem for clinical anti-infective treatments.
Yuhang Wang +8 more
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Biologie in unserer Zeit, 2018 Pflanzen können von einer Vielzahl an Pathogenen befallen werden, die schwerwiegende Krankheiten auslösen und besonders bei Nutzpflanzen zu starken Ernteverlusten beitragen. CRISPR/Cas‐Systeme verändern die Angriffsstellen dieser Pathogene hochpräzise, sodass ein Befall nicht mehr stattfinden kann – eine Entwicklung, die als Revolution in der ...
Patrick Schindele +2 more
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Molecules, 2022 The CRISPR-Cas system is a bacterial and archaea adaptive immune system and is a newly recognized mechanism for controlling antibiotic resistance gene transfer. Acinetobacter baumannii (A.
Tingting Guo +8 more
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Adaptation in CRISPR-Cas Systems [PDF]
Molecular Cell, 2016 Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system in prokaryotes. The system preserves memories of prior infections by integrating short segments of foreign DNA, termed spacers, into the CRISPR array in a process termed adaptation.
Samuel H. Sternberg +3 more
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CRISPR-Cas Systems in Streptococci [PDF]
Current Issues in Molecular Biology, 2019 Streptococci are one of the most important and common constituents of the host's microbiota and can colonize and live in the upper respiratory and urogenital tract of humans and animals. The CRISPR-Cas systems (i.e., clustered regularly interspaced short palindromic repeat, with CRISPR-associated proteins) found in bacteria and archaea provide sequence-
Tao, Gong +7 more
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