Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity [PDF]
, 2015 EC is supported by the Alexander von Humboldt Foundation, the German Federal Ministry for Education and Research, the Helmholtz Association, the Göran Gustafsson Foundation, the Swedish Research Council, the Kempe Foundation and Umeå University.
White, Malcolm F. +4 more
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Research Progress on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-Associated Protein (Cas)-Isothermal Amplification in the Detection of Foodborne Pathogens [PDF]
Shipin KexueFood safety incidents caused by foodborne pathogens have attracted widespread attention. In order to ensure food safety, it is essential to adopt effective detection means.
ZHANG Qi, PANG Lidong, SU Qunchao, SONG Danliangmin, YANG Xinyan, JIANG Yujun, ZHANG Wei
doaj +1 more source
Research progress of CRISPR/Cas systems in nucleic acid detection of infectious diseases
iLABMED, 2023 Infectious diseases are a serious threat to human health, and accurate, rapid and convenient early detection of pathogens is the first step of active treatment.
Jinying Dong, Yuguang Du, Lei Zhou
doaj +1 more source
The structural biology of CRISPR-Cas systems [PDF]
Current Opinion in Structural Biology, 2015 Prokaryotic CRISPR-Cas genomic loci encode RNA-mediated adaptive immune systems that bear some functional similarities with eukaryotic RNA interference. Acquired and heritable immunity against bacteriophage and plasmids begins with integration of ∼30 base pair foreign DNA sequences into the host genome.
Jiang, Fuguo, Doudna, Jennifer A
openaire +5 more sources
CRISPR interference : a structural perspective [PDF]
, 2013 This article was made open access through BIS OA funding. The laboratory is funded by grants from the Biotechnology and Biological Sciences Research Council (BBSRC).CRISPR (cluster of regularly interspaced palindromic repeats) is a prokaryotic adaptive ...
Naismith, Jim +2 more
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Phylogenetic Distribution of CRISPR-Cas Systems in Staphylococcus lugdunensis
Microbiology Spectrum, 2021 Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) genes (CRISPR-Cas) are present in many bacterial genomes with functions beyond adaptive immunity.
Cheng-Yen Kao +4 more
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Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]
, 2013 The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
Zhang, Jing, White, Malcolm F.
core +1 more source
CRISPR RNA biogenesis by a Cas6 nuclease [PDF]
, 2015 Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated (Cas) proteins form the basis of a prokaryotic adaptive immune system.
Sokolowski, Richard D.
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Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein
mBio, 2017 CRISPR (clustered regularly interspaced short palindromic repeat)-Cas adaptive immune systems are prevalent defense mechanisms in bacteria and archaea.
April Pawluk +6 more
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Frontiers in Microbiology, 2021 Staphylococcus aureus (S. aureus), which is one of the most important species of Staphylococci, poses a great threat to public health. Clustered regularly interspaced short palindromic repeats (CRISPR) and their CRISPR-associated proteins (Cas) are an ...
Ying Wang +6 more
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