Results 201 to 210 of about 321,595 (358)
CRISPR-Based Directed Evolution for Crop Improvement
, 2019 Haroon Butt +3 more
openalex +2 more sources
Advanced Science, EarlyView.Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
CRISPR/CAS9-based gene editing in cancer therapy: A systematic review and meta-analysis on current status and future directions. [PDF]
Medicine (Baltimore)Rehman SU, Abbas GH.
europepmc +1 more source
A Serum Resistant Polymer with Exceptional Endosomal Escape and mRNA Delivery Efficacy for CRISPR Gene Therapy [PDF]
Jia Lv +8 more
openalex +1 more source
SHERLOCK: nucleic acid detection with CRISPR nucleases
Nature Protocols, 2019 M. Kellner +4 more
semanticscholar +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
Advanced Science, EarlyView.This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
G3: Genes, Genomes, Genetics, 2020 Nikolay P. Kandul +5 more
doaj +1 more source
Versatile genome editing using Type I-E CRISPR-Cas3 in rice. [PDF]
Plant Cell PhysiolSaika H +6 more
europepmc +1 more source