Results 111 to 120 of about 6,381,415 (310)

Photoexcited LMCT of Cu2+ perfluorocarboxylate for initiating efficient defluorination

open access: yesNature Communications
Per- and polyfluoroalkyl substances are widely distributed persistent pollutants in water resources that pose serious environmental and health threats. Current per- and polyfluoroalkyl substance destruction strategies are energy-intensive, nonselective ...
Jialei Guo   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Ambient Water Quality Criteria Recommendations: Information Supporting the Development of State and Tribal Nutrient Criteria for Lakes and Reservoirs in Nutrient Ecoregion III

open access: yes, 2001
This document presents the Environmental Protection Agency's nutrient criteria for Lakes and Reservoirs in Nutrient Ecoregion ...
United States Environmental Protection Agency; Office of Water
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A Multi-Criteria Decision Framework for Animal Welfare Policy [PDF]

open access: yes
Policy decisions aimed at improving farm animal welfare involve balancing several competing objectives. Not only do such decisions involve tradeoffs between social, ethical, economic and welfare considerations, animal welfare itself is a multi ...
Hellstrom, J., Bicknell, Kathryn
core  

Harnessing the criteria matrix : a tool for equity - worksheet

open access: yes
From Oregon State University's Search Advocate Program. Worksheet to go with Harnessing the Criteria Matrix presentation (see related works below).Learning Outcomes - At the end of this session you will be prepared to: • Explain why the criteria matrix ...
Gillies, Anne, Oregon State University
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Multiple criteria decision making

open access: yes, 1973
817 p., fig., ref. bib. : 17 p.1/2This volume is the direct result of a seminar on Multiple Criteria Decision Making held at the University of South Carolina on October 26-27, 1972. Support for this seminar and for production of this book was provided by
ZELENY, Milan, COCHRANE, James L.
core  

Microbial eukaryote community succession over hundreds of years in Chinese lakes

open access: yesEcological Indicators
Microbial eukaryotes play critical roles in maintaining the health and stability of lake ecosystems. Consequently, investigating the spatial and temporal evolution of microbial eukaryotic community structures and associated environmental drivers can ...
Yi Li   +7 more
doaj   +1 more source

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