Results 71 to 80 of about 988,489 (304)

Avaliação do funcionamento cognitivo por meio do CAT-A: evidências de validade Cognitive assessment using the CAT-A: validity evidence

Psicologia: Reflexão e Crítica, 2013
O objetivo desse estudo foi trazer evidências de validade do CAT-A para avaliação do funcionamento cognitivo em crianças. Correlacionou-se indicadores cognitivos no CAT-A; DFH e Rorschach no Sistema Compreensivo. Inicialmente, com base no DFH, selecionou-
Maria de Fátima Xavier, Anna Elisa de Villemor-Amaral   +1 more
doaj  

Cross-cultural adaptation and psychometric evaluation of a German version of the Activity Patterns Scale (APS-GE) in a large sample of patients with chronic musculoskeletal pain

Frontiers in Pain Research
BackgroundAcknowledging the multidimensionality of pain-related activity patterns led to the development of a new self-report instrument, the Activity Patterns Scale (APS), linking activity pacing to underlying goals.
Anne Kästner, Margarete Donhauser, Inga von Freytag-Löringhoff, Frank Petzke   +3 more
doaj   +1 more source

Validity of semiclassical gravity in the stochastic gravity approach

, 2005
In semiclassical gravity the back-reaction of the classical gravitational field interacting with quantum matter fields is described by the semiclassical Einstein equations.
Verdaguer, E.
core   +2 more sources

The psychometric properties of GHQ for detecting common mental disorder among community dwelling men in Goa, India. [PDF]

, 2017
BACKGROUND: There have not been many attempts to validate screening measures for common mental disorders (CMD) in low- and middle-income countries. The aim of this study was to examine the criterion validity of the General Health Questionnaire 12 (GHQ-12)
Endsley, Paige, Nadkarni, Abhijit, Weobong, Benedict   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Development and validation of the guideline for reporting evidence-based practice educational interventions and teaching (GREET) [PDF]

, 2016
Background The majority of reporting guidelines assist researchers to report consistent information concerning study design, however, they contain limited information for describing study interventions.
Galipeau, James, Glasziou, Paul, Lewis, Lucy K., McEvoy, Maureen P., Moher, David, Phillips, Anna C., Tilson, Julie K., Williams, Marie T.   +7 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

上肢动作研究测试量表评定亚急性期缺血性卒中患者偏瘫侧上肢及手功能的信效度和敏感性研究 (Study on the Reliability, Validity, and Sensitivity of Action Research Arm Test Scale in Evaluating the Function of Hemiplegic Upper Limb and Hand in Subacute Stage Ischemic Stroke Patients)

Zhongguo cuzhong zazhi
目的 探讨上肢动作研究测试（action research arm test，ARAT）量表应用于亚急性期缺血性卒中患者上肢及手功能障碍评定的效度、信度和敏感性。 方法 本研究招募2020年1月—2022年5月于首都医科大学附属北京天坛医院等17家医院住院的300例缺血性卒中患者，并由两名评定者分别对受试者进行ARAT量表评估。同时以Fugl-Meyer运动功能评定量表上肢部分（Fugl-Meyer assessment-upper extremity，FMA-UE ...
吴娱倩1，张玉梅1，臧大维1，2，3，范小伟4，王安心2，3，张晓丽2，3，孟霞2，3 (WU Yuqian1, ZHANG Yumei1, ZANG Dawei1,2,3, FAN Xiaowei4, WANG Anxin2,3, ZHANG Xiaoli2,3, MENG Xia2,3 )
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source