Results 71 to 80 of about 323,447 (317)

Criterion validity of manual assessment of spinal stiffness [PDF]

Manual Therapy, 2014
Assessment of spinal stiffness is widely used by manual therapy practitioners as a part of clinical diagnosis and treatment selection. Although studies have commonly found poor reliability of such procedures, conflicting evidence suggests that assessment of spinal stiffness may help predict response to specific treatments.
Julie M. Fritz, Julie M. Fritz, John D. Childs, Theodore Croy, Shane L. Koppenhaver, Jeffrey J. Hebert, Greg Kawchuk, Deydre S. Teyhen   +7 more
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A Missing Data Approach to Correct for Direct and Indirect Range Restrictions with a Dichotomous Criterion: A Simulation Study. [PDF]

PLoS ONE, 2016
A recurring methodological problem in the evaluation of the predictive validity of selection methods is that the values of the criterion variable are available for selected applicants only.
Andreas Pfaffel, Marlene Kollmayer, Barbara Schober, Christiane Spiel   +3 more
doaj   +1 more source

Dynamical Density Fluctuation of Superfluids near Critical Velocities [PDF]

, 2010
We propose a stability criterion of superfluids in condensed Bose-Einstein systems, which incorporates the spectral function or the autocorrelation function of the local density. Within the Gross-Pitaevskii-Bogoliubov theory, we demonstrate the validity of our criterion for the soliton-emission instability, with use of explicit forms of zero modes of ...
arxiv   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Using machine-learning strategies to solve psychometric problems

Scientific Reports, 2022
Validating scales for clinical use is a common procedure in medicine and psychology. Through the application of computational methods, we present a new strategy for estimating construct validity and criterion validity.
Arthur Trognon, Youssouf Ismail Cherifi, Islem Habibi, Loïs Demange, Cécile Prudent   +4 more
doaj   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

On badly approximable numbers [PDF]

arXiv, 2020
Motivated by a wonderful paper by Ngoc Ai Van Nguyen, Anthony Po\"els and Damien Roy, where a powerful method was introduced, we prove a criterion for a vector $\pmb{\alpha}\in \mathbb{R}^d$ to be a badly approximable vector. Moreover we construct certain examples which show that a more general version of our criterion is not valid.
arxiv  

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Avaliação do funcionamento cognitivo por meio do CAT-A: evidências de validade Cognitive assessment using the CAT-A: validity evidence

Psicologia: Reflexão e Crítica, 2013
O objetivo desse estudo foi trazer evidências de validade do CAT-A para avaliação do funcionamento cognitivo em crianças. Correlacionou-se indicadores cognitivos no CAT-A; DFH e Rorschach no Sistema Compreensivo. Inicialmente, com base no DFH, selecionou-
Maria de Fátima Xavier, Anna Elisa de Villemor-Amaral   +1 more
doaj