Results 61 to 70 of about 15,117,110 (236)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Asmptotically Plane Wave Spacetimes [PDF]

open access: yes, 2009
In this thesis we study aspects of plane wave spacetimes in the hope of shedding light of the nature of holography for plane waves. In particular, we would like to understand better the space of asymptotically plane wave solutions.
LE-WITT, JULIAN,ALEXANDER   +1 more
core  

Prediction of fatigue crack initiation life in railheads using finite element analysis

open access: yesAin Shams Engineering Journal, 2018
The current study introduced a numerical procedure to study fatigue crack initiation life in railheads. It was mainly performed by a three-dimensional (3D) explicit finite element (FE) model that accounts for bending stresses due to global dynamic ...
H.M. El-sayed   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

T-L Plane Abstraction-Based Energy-Efficient Real-Time Scheduling for Multi-Core Wireless Sensors

open access: yesSensors, 2016
Energy efficiency is considered as a critical requirement for wireless sensor networks. As more wireless sensor nodes are equipped with multi-cores, there are emerging needs for energy-efficient real-time scheduling algorithms. The T-L plane-based scheme
Youngmin Kim   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

“A review of the external oblique intercostal plane block - a novel approach to analgesia for upper abdominal surgery”

open access: yes, 2022
To The Editor - The external oblique intercostal (EOI) plane block represents a novel approach to regional anaesthesia for upper abdominal surgeries that have previously relied upon neuraxial or deep plane block regional techniques or the use of patient ...
Erskine, RN, White, L
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Failure Criterion for Brick Masonry: A Micro-Mechanics Approach

open access: yesStudia Geotechnica et Mechanica, 2015
The paper deals with the formulation of failure criterion for an in-plane loaded masonry. Using micro-mechanics approach the strength estimation for masonry microstructure with constituents obeying the Drucker-Prager criterion is determined numerically ...
Kawa Marek
doaj   +1 more source

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