Results 131 to 140 of about 7,934,690 (311)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Tibial scoring as a predictor for amputation-free survival in critical limb ischemic patients

open access: yesJournal of the Arab Society for Medical Research
Background/aim Evaluating the risk of amputation in patients with peripheral arterial disease (PAD) is essential. A critical Limb Ischemic patient (CLI) is known as end stage of PAD.
Yehia K. Sadek   +2 more
doaj   +1 more source

Critical criminology [PDF]

open access: yes, 2014
Critical Criminology is now a well-established—if heterogeneous and contentious—field of study. The work of critical criminologists supports numerous international journals, regional organizations, and global conferences.
Dragiewicz, M, DeKeseredy, WS
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Una poética de la comparación: crítica y ficción en María Gainza

open access: yesCuadernos LIRICO
In this article we will analyze the procedure of construction of a fictional character that allows the author María Gainza to cement a position of critical enunciation in the contemporary art world.
Laura Gentilezza
doaj   +1 more source

Critical evaluation [PDF]

open access: yes, 2009
Web-based materials examining critical evaluation in the social ...
Bangor University, Eileen Tilley
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

DOTS-LCCI - Dependable Off-The-Shelf based middleware systems for Large-scale Complex Critical Infrastructures [PDF]

open access: yes, 2010
Large scale Complex Critical Infrastructures (LCCIs), such as water and power supply plants, and transport infrastructures (e.g., airports and seaports), play a key role into several fundamental human activities.
RUSSO, STEFANO
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Paradigms of approaches to research

open access: yesBangabandhu Sheikh Mujib Medical University Journal
Not ...
Tanvir C Turin   +2 more
doaj  

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