Results 31 to 40 of about 269,281 (230)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Research on the ejection performance of an ejector with low pressure and back pressure
Scientific ReportsThis study investigates the influence of back pressure on the mass ejection coefficient (u) of low-pressure methane-air ejectors through a combined approach of one-dimensional mathematical modeling and computational fluid dynamics (CFD) simulations.
Cong Chen, Haijing Liu, Pengfei Duan
doaj +1 more source
Toxicology ReportsLower back pain is among the top ten reasons patients visit the emergency department (ED). Tizanidine, a centrally acting alpha-2 adrenergic receptor agonist, is commonly prescribed for managing spasticity in patients with cerebral or spinal injuries. It
Muhammad Abd Ur Rehman +3 more
doaj +1 more source
New cycloid rotor profiles design under different rolling circle radii for Roots vacuum pumps
SN Applied Sciences, 2022 Article highlights 1. Two new rotor profiles are proposed and designed to improve the performance for Roots vacuum pump. 2. For the new rotor profile formed by a large rolling circle, its volume utilization rate is greater than 60%, which can pump more ...
Zhengqing Li, Xiaojun Wang
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Results in EngineeringAerospike nozzles, characterized by its distinct structure diverging from the conventional bell nozzle, are commonly employed in aerospace propulsion systems. This structural configuration confers performance advantages under specific operating condition.
Changchao Liu +5 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Case Studies in Thermal EngineeringIn longitudinally ventilated tunnel fires, subcritical ventilation is widely used in the early stage of accidents to maintain smoke stratification. Due to the stack effect, the smoke movement in inclined tunnels is different from that in horizontal ...
Haibin Wei +6 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source