Results 51 to 60 of about 8,514,772 (261)
New cycloid rotor profiles design under different rolling circle radii for Roots vacuum pumps
SN Applied Sciences, 2022 Article highlights 1. Two new rotor profiles are proposed and designed to improve the performance for Roots vacuum pump. 2. For the new rotor profile formed by a large rolling circle, its volume utilization rate is greater than 60%, which can pump more ...
Zhengqing Li, Xiaojun Wang
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Blood Pressure Control in Patients with Diabetic Kidney Disease [PDF]
, 2022 Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease. Blood pressure (BP) control can reduce the risks of cardiovascular (CV) morbidity, mortality, and kidney disease progression.
유태현
core +1 more source
, 1935 This collection contains documents and correspondence from the collection of Phillip Goldstein Back (1902-1979), a long-time resident of Little Rock and prominent Jewish ...
Back, Phillip Goldstein, 1902-1979
core +1 more source
Case Studies in Thermal EngineeringIn longitudinally ventilated tunnel fires, subcritical ventilation is widely used in the early stage of accidents to maintain smoke stratification. Due to the stack effect, the smoke movement in inclined tunnels is different from that in horizontal ...
Haibin Wei +6 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Maximum allowable pressure during heavy slurry displacement
Journal of Petroleum Exploration and Production Technology, 2020 Heavy slurry pumping is facing enormous problems concerning pressure generation and casing limitations. Pumping high-density cement throughout narrow column, throttled at their extremity by the float equipment will generate more pressure, and could push ...
Abdeslem Leksir
doaj +1 more source