Results 51 to 60 of about 271,158 (273)
Maximum allowable pressure during heavy slurry displacement
Journal of Petroleum Exploration and Production Technology, 2020 Heavy slurry pumping is facing enormous problems concerning pressure generation and casing limitations. Pumping high-density cement throughout narrow column, throttled at their extremity by the float equipment will generate more pressure, and could push ...
Abdeslem Leksir
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Development of LP Blade Module for High Back Pressure-Aerodynamic Design
, 2017 In steam turbine power plants, the appropriate design of the last stage blades is critical in determining the plant efficiency and reliability. The development of LP module for desert applications is finding applications for a number of industrial steam ...
null Ambrish, Nand Kumar Singh
core +1 more source
Frontiers in Built Environment, 2020 Monitoring ballast support condition and improving current sub-structure and ballast maintenance strategies is critical to ensuring safe and efficient railroad operations.
Camila Pereira Silva +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Energy transfer in color-tunable water-dispersible Tb-Eu codoped CaF2 nanocrystals [PDF]
, 2016 The development of highly luminescent water-dispersible biocompatible nanoparticles is a hot topic in biomedical research. Here, we report about the study of the energy transfer process between Tb3+ and Eu3+ in calcium fluoride nanoparticles.
TRAVE, Enrico +14 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A critical analysis of Iranian buy-back transactions in the context of international petroleum contractual systems [PDF]
, 2008 This research critically examines the Iranian petroleum contractual system from its birth to the present, and considers its future evolution. Initially, it reviews the development of oil contracts, from the early concessions until the annulment of all ...
Kakhki, Mohammad Mehdi Hedayati
core
Static back-pressure effects on the performance of a dual-fuel engine
, 2021 The use of fossil fuels and their impact on humans and nature is becoming a bigger concern worldwide. An interesting concept to lower polluting emissions coming from maritime engines is the combined use of a dual-fuel engine and an underwater exhaust ...
Peet, Wieger (author)
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source