Results 191 to 200 of about 1,997,752 (267)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Moral Courage as a Predictor of Moral Comfort in Critical Care Nurses. [PDF]

J Nurs Manag
Zagheri-Tafreshi M, Etemadi S, Babaei P, Barkhordari-Sharifabad M.   +3 more
europepmc   +1 more source

The Impact of Early Palliative Care Consultation on Length of Stay for Critically Ill Adults in the Intensive Care Unit

Stephen Caplan, Patricia C. Pawlow
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Critical care transfers of ventilator-dependent patients from operating theatres to Critical Care Units in a South African Metropole. [PDF]

Afr J Emerg Med
Cloete E, Badenhorst JJ, Reed AR.
europepmc   +1 more source

Quality and safety of inter-hospital transfers care of critically ill patients from rural community hospitals to the Tertiary Regional Hospital in Thailand : a focused ethnographic study

, 2018
Busarin Eiu-Seeyok
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Critical Care After Thrombolytic Therapy in Acute Stroke: Who Really Needs the ICU? [PDF]

J Clin Med
Moore KG, Harshaw NS, LaRosa SK, Indeck D, Cross D, Chiota-McCollum N, Perea LL.   +6 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Methylene blue in the critical care setting. [PDF]

World J Crit Care Med
Elmati PR, Nagaradona T, Raghove V, Jagirdhar GSK, Surani S.   +4 more
europepmc   +1 more source