Results 201 to 210 of about 5,260,453 (314)

Future of critical care: a blueprint for building sustainable cardiac critical care capacity. [PDF]

Ann Transl Med
Franko L, Nikolic I, Kwo J, Bagchi A, D'Alessandro D, Sundt T, Shelton KT.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Socioeconomic Status, Rurality, and Pediatric Critical Care Admission.

JAMA Netw Open
Bone JN, Shen Y, Harden S, Retallack J, Carwana M, Murthy S, Muttalib F.   +6 more
europepmc   +1 more source

Assessment of critical care education in the context of a Tele-ICU implementation. [PDF]

ATS Sch
Cunha MCAD, Cavalcante Neto PM, Campos CV, Costa ELV, Oliveira PR, Yokoyama TS, Correia JMO, Savastano CP, Ferreira JC, Amato MBP, Carvalho CRR.   +10 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Exploring the Relationship Between Alarm Fatigue and Compassion Fatigue Among Critical Care Nurses. [PDF]

Nurs Crit Care
Ceran FN, Güneş Ü.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Challenges and Recommendations for Integrating Circadian Medicine in Critical Care: A Roadmap. [PDF]

Chest
Hiemstra FW, González LB, Engelhardt LJ, Hancke L, Pilz LK, Adler AI, Dashti HS, Drouot X, Kitchen GB, Knauert MP, Kramer A, Lipton JO, Luetz A, Maas MB, Pajor NM, Parthasarathy S, Spies C, van Westerloo DJ, Felten M, Klerman EB, Ray DW, Ruben MD, Roenneberg T, Kervezee L.   +23 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source