Results 81 to 90 of about 1,997,752 (267)

Deciphering Cuproptosis in Sepsis: Mechanisms, Consequences, and Therapeutic Opportunities

open access: yesJournal of Inflammation Research
Ruimin Tan,1,2 Kexin Wen,1,2 Tianyu Zhao,2,3 He Guo,2,4 Xumin Han,2,4 Jiakai Wang,2,4 Chen Ge,2 Quansheng Du2 1School of Clinical Medical, North China University of Science and Technology, Tangshan, Hebei, People’s Republic of China; 2Critical Care ...
Tan R   +7 more
doaj  

Septic Shock and Multiorgan Failure Related to Liver Abscess Caused by Fish Bone Penetration of Duodenal Wall

open access: yesCase Reports in Gastrointestinal Medicine
We report an intriguing case of an 80-year-old male presented with high-grade fever and severe upper abdominal pain. An abdominal ultrasound indicated a deep-seated abscess in the Segment IV of liver. An elusive diagnosis was made after Contrast Enhanced
Md. Atiquzzaman   +9 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Trimming the need for invasive ventilation: pragmatic critical care during the COVID-19 pandemic [PDF]

open access: bronze, 2020
Connor P. Oates   +3 more
openalex   +1 more source

The Reviewer Academy of the Society of Critical Care Medicine: Key Principles and Strategic Plan [PDF]

open access: green, 2023
Peta Alexander   +24 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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