FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
The Value of Glycemic Gap for Predicting Mortality in ICU in Patients With and Without Diabetes
Journal of Diabetes ResearchConclusion: The glycemic GAP between the mean level of blood glucose within the first 7 days in ICU and ADAG was independently associated with 28-day mortality of critically ill patients, which was different between patients with and without diabetes ...
Ran Lou +10 more
doaj +1 more source
Endobronchial Lipoma: A Rare Cause of Bronchial Stenosis or Obstruction
Canadian Respiratory Journal, 2023 Endobronchial lipoma (EL) is a rare benign tumor characterized by tracheobronchial smooth-surfaced mass, often resulting in bronchial obstruction without standard guidelines for management.
Jian Chen +9 more
doaj +1 more source
Increasing Critical Care Nurse Engagement of Palliative Care During the COVID-19 Pandemic.
Critical Care Nurse, 2020 BACKGROUND The coronavirus disease 2019 pandemic has led to escalating infection rates and associated deaths worldwide. Amid this public health emergency, the urgent need for palliative care integration throughout critical care settings has never been ...
W. Rosa, B. Ferrell, Clareen A. Wiencek
semanticscholar +1 more source
Hospital Pharmacy, 2015 Advancement in health care technology and new drugs continue to impact the complexity of patient care provided in the intensive care unit (ICU). As with all patient care directives, optimizing rational therapy while preventing errors and adverse events remains premier.
openaire +3 more sources
What is the potential of distance education for learning and practice development in critical care nursing in the South Island of New Zealand? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education in Adult Education at Massey University [PDF]
, 2003 This thesis explores the potential of distance approaches to teaching and learning in post registration nursing education within the context of critical care nursing practice.
Hardcastle, Jane
core
Humanizing critical care [PDF]
, 2017 Sleep is important for human neurocognitive, emotional and physical health. Increasing evidence shows that the intensive care unit environment is disruptive to sleep patterns. Such disruption is unpleasant to patients, but mounting evidence suggests that
Bion, V, Montgomery, H
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
The Chelsea Critical Care Physical Assessment Tool (CPAx): validation of an innovative new tool to measure physical morbidity in the general adult critical care population; an observational proof-of-concept pilot study. [PDF]
, 2013 Objective To develop a scoring system to measure physical morbidity in critical care – the Chelsea Critical Care Physical Assessment Tool (CPAx). Method The development process was iterative involving content validity indices (CVI), a focus group and an ...
Corner, EJ +6 more
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source