Results 131 to 140 of about 895,229 (373)

Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit [PDF]

open access: yes, 2002
INTRODUCTION: The diagnosis of sepsis in critically ill patients is challenging because traditional markers of infection are often misleading. The present study was conducted to determine the procalcitonin level at early diagnosis (and differentiation ...
BalcI, Canan   +4 more
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

open access: yes, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J   +2 more
core   +2 more sources

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

open access: yesFEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

The intensive care medicine clinical research agenda in paediatrics [PDF]

open access: yes, 2017
BACKGROUND: Intensive Care Medicine set us the task of outlining a global clinical research agenda for paediatric intensive care (PIC). In line with the clinical focus of this journal, we have limited this to research that may directly influence ...
Argent, A   +9 more
core  

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Increasing Early Mobility of Patients in the Intensive Care Unit [PDF]

open access: yes, 2018
This project occurred in a 35-bed intensive care unit at a level II trauma center in central California. The purpose of this project was to strengthen the implementation of evidence-based initiatives promoted by the Society of Critical Care Medicine ...
Gilliam, Wendie
core   +1 more source

Parents’ and carers’ experiences of transition and aftercare following a child's discharge from a paediatric intensive care unit to an in-patient ward setting:A qualitative systematic review [PDF]

open access: yes, 2019
Objectives: To explore parents’ experiences of transition and aftercare following their child’s discharge from a pediatric intensive care unit to an inpatient ward.Methods: A qualitative systematic review was conducted.
Evans, Catrin   +2 more
core   +2 more sources

Analysis of fourteen cases of snake bite envenomation admitted in ICU of a tertiary care hospital of Bangladesh : A retrospective observational study [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Background: Effective management strategies for snake envenomation are critical for reducing the morbidity and mortality as treatment gaps, delays, and reliance on traditional healers frequently exacerbate outcomes.
AKM Rahman   +7 more
doaj   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

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