Results 131 to 140 of about 357,533 (318)

Critical care medicine and intensive care in obstetrics: in search of a legacy

Revista colombiana de obstetricia y ginecologia
Contrary to popular belief, the true architect of success in the care of critically ill patients and their families is not the use of complex interventions or advanced hemodynamic or multimodal monitoring. It is human talent that, with determination, vocation, and dedication, provides every day the best possible care in pursuit of the best clinical ...
Carlos Fernando, Grillo-Ardila, Luis Carlos, Triana-Moreno, Oscar Orlando, Sanabria-Rodríguez   +2 more
openaire   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Implementation of Acupuncture Treatment in the Modern Operating Environment: Our Reply to Study by Zou X et al [Letter]

Journal of Pain Research
Pradipta Bhakta,1 Habib Md Reazaul Karim,2 Mohan Mugawar,1 Brian O’Brien31Department of Anesthesiology and Intensive Care, Midland Regional Hospital Tullamore, Tullamore, Ireland; 2Department of Anesthesiology, Critical Care, and Pain Medicine,
Bhakta P, Karim HMR, Mugawar M, O'Brien B   +3 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Predictive Value of Combined Serum NOX4, Gal-13, and Cyclophilin A for Prognosis in Severe Pneumonia

International Journal of General Medicine
Qindi Liu,1 Huanghuang Meng,2 Hong Sun3 1Department of Respiratory and Critical Care Medicine, Ganzhou City Fifth People’s Hospital, Ganzhou, Jiangxi, 341099, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Ganzhou ...
Liu Q, Meng H, Sun H
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Advancing practice in critical care nursing. [PDF]

This thesis presents a body of publications in the area of critical care nursing, for the consideration of the award Doctor of Philosophy by publication.
Christensen, Martin
core  

FGF7 mitigates airway inflammation and epithelial injury in cigarette smoke-induced COPD model

Frontiers in Immunology
BackgroundChronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease marked by persistent airway limitation. Airway epithelial injury is pivotal in the onset and progression of COPD.
Xinji Gong, Jingwen Li, Haitao Wang, Xi Luo, Xinying Hu, Jie Shen, Wenting Jia, Qiufeng Wan, Shareli Caikai, Zhijin Guo, Fang Yan, Ying Zhang, Feng Sun, Sicheng Xu   +13 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source