Results 141 to 150 of about 895,229 (373)

A readers' guide to the interpretation of diagnostic test properties: clinical example of sepsis [PDF]

, 2018
Background: One of the most challenging practical and daily problems in intensive care medicine is the interpretation of the results from diagnostic tests.
Bachmann, Lucas, Fischer, Joachim, Jaeschke, Roman   +2 more
core  

Eighth World Congress of Intensive and Critical Care Medicine, 28 October-1 November 2001, Sydney, Australia: Harm minimization and effective risk management. [PDF]

, 2002
Naresh Ramakrishnan
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

2019 World Congress of Intensive Care: Hosted by the Australian and New Zealand Intensive Care Society, the Australian College of Critical Care Nurses, and the World Federation of Societies of Intensive and Critical Care Medicine, 14–18 October 2019, Melbourne Convention and Exhibition Centre, Melbourne, Australia [PDF]

, 2020

openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Intelligent decision support in Intensive Care : towards technology acceptance [PDF]

, 2012
Decision support technology acceptance is a critical factor in the success of the adoption this type of systems by the users. INTCARE is an intelligent decision support system for intensive care medicine.
Abelha, António, Machado, José Manuel, Neves, José, Portela, Filipe, Rua, Fernando, Santos, Manuel Filipe, Silva, Álvaro   +6 more
core  

Best evidence in critical care medicine Selective digestive decontamination decreases mortality and morbidity in the intensive care [PDF]

, 2004
Osama Almuslim, Ron Butler
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Implications of the sepsis-3 definition on nursing research and practice [PDF]

, 2017
In February 2016, the Society of Critical Care Medicine and the European Society of Intensive Care Medicine announced a striking change in the sepsis definition. The new definition, known as Sepsis-3, replaces the SIRS criteria with the SOFA Score.
Peach, Brian C.
core   +1 more source