Results 81 to 90 of about 2,363,196 (290)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Self-field effects upon the critical current density of flat superconducting strips

, 2004
We develop a general theory to account self-consistently for self-field effects upon the average transport critical current density Jc of a flat type-II superconducting strip in the mixed state when the bulk pinning is characterized by a field-dependent ...
Ali A Babaei Brojeny, Campbell A M, Clem J R Timmerhaus K D O’Sullivan W J Hammel E F, Elistratov A A, John R Clem, Provost J, Suenaga M   +6 more
core   +1 more source

Current-driven skyrmion Depinning in Magnetic Granular Films [PDF]

, 2019
We consider current-driven motion of magnetic skyrmions in granular magnetic films. The study uses micromagnetic modeling and phenomenological analysis based on the Thiele formalism.
Abbout, A., Brataas, A., Manchon, A., Salimath, A.   +3 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Influence of vortex-vortex interaction on critical currents across low-angle grain boundaries in YBa2Cu3O7-delta thin films

, 2000
Low-angle grain boundaries with misorientation angles theta < 5 degrees in optimally doped thin films of YBCO are investigated by magnetooptical imaging.
A. A. Polyanskii, A. Gurevich, A. Gurevich, A. Gurevich, A. P. Sutton, A. Pruymboom, B. H. Moeckly, Ch. Jooss, Ch. Jooss, D. Dimos, D. N. Basov, E. H. Brandt, H. Hilgenkamp, H. Hilgenkamp, H. Kronmüller, J. A. Alarco, J. Albrecht, J. B. Hirth, J. Halbritter, J. L. Tallon, J. M. Huijbregtse, J. Mannhart, K. E. Gray, L. A. Dorosinskii, M. F. Chisholm, N. F. Heinig, P. G. de Gennes, R. Gross, R. Gross, R. Wijngaarden, S. Leonhardt, Th. Schuster, Z. G. Ivanov   +32 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Wet Chemical Method ZnF2 Interlayer for High Critical Current Density Lithium Metal Batteries Utilizing Ba and Ta–Doped Li7La3Zr2O12 Garnet Solid Electrolyte

Advanced Materials Interfaces
Li metal batteries with garnet‐type solid electrolytes have the potential to increase specific energy and power densities of current Li‐ion batteries.
Subhajit Sarkar, Vishnu Surendran, Venkataraman Thangadurai   +2 more
doaj   +1 more source

Low-temperature Synthesis of FeTe0.5Se0.5 Polycrystals with a High Transport Critical Current Density

, 2011
We have prepared high-quality polycrystalline FeTe0.5Se0.5 at temperature as low as 550{\deg}C. The transport critical current density evaluated by the current-voltage characteristics is over 700 A/cm2 at 4.2 K under zero field, which is several times ...
Ding Q, Guo J G, Gurevich A, Krzton-Maziopa A Shermadini Z Pomjakushina E Pomjakushin V Bendele M Amato A Khasanov R Luetkens H Conder K, Nakajima Y, Ogino H, Ozaki T Deguchi K Mizuguchi Y Kawasaki Y Tanaka T Yamaguchi T Tsuda S Kumakura H Takano Y, Ozaki T Deguchi K Mizuguchi Y Kumakura H Takano Y, Qi Y P, Qing-Ping Ding, Ren Z A, Shyam Mohan, Tamegai T, Toshihiro Taen, Tsuyoshi Tamegai, Wang A F, Wang L, Yadav C S, Yasuyuki Nakajima, Yeh K W, Yuji Tsuchiya   +20 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Influence of Sintering Temperature on the Transport Properties of GdBa₂Cu₃O₇ Superconductor Prepared from Nano-Powders via the Co-Precipitation Method

Inorganics
This study examines the influence of sintering temperature on the structural and transport properties of GdBa2Cu3O7 (Gd123) superconductors prepared from nano-sized precursors via the co-precipitation method. The metal-oxalate precursor (average particle
Ahmed Al-Mobydeen, Mohammed M. Alawamleh, Sondos Shamha, Ehab AlShamaileh, Iessa Sabbe Moosa, Jamal Rahhal, Mike Haddad, Wala`a Al-Tarawneh, Yousef Al-Dalahmeh, Imad Hamadneh   +9 more
doaj   +1 more source