Results 81 to 90 of about 8,410,995 (293)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Critical Data Studies 2017 - COMS5225

, 2019
Theoretical debates, research approaches and discursive regimes pertaining to the datafication of everyday life, data and living environments, and the quantified control of the future. Emphasis on the production of databased knowledge and the influence data have on the material and social world.
openaire   +1 more source

User-oriented security supporting inter-disciplinary life science research across the grid [PDF]

, 2007
Understanding potential genetic factors in disease or development of personalised e-Health solutions require scientists to access a multitude of data and compute resources across the Internet from functional genomics resources through to epidemiological ...
Ajayi, O., Jiang, J., Sinnott, R.O., Stell, A.J., Watt, J.   +4 more
core   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

What are the important factors in health-related quality of life for people with aphasia? A systematic review [PDF]

, 2012
Objective: To determine factors associated with or predictive of poor health-related quality of life (HRQL) in people with aphasia poststroke. Better understanding of these factors can allow better targeting of rehabilitation programs.
Ahlsio, Angeleri, Astrom, Astrom, Bays, Benejam, Berzon, Best, Bose, Bullinger, Callahan, Carod-Artal, Carod-Artal, Clarke, Code, Code, Code, Counsell, Cruice, Cruice, Cruice, Cruice, Cruice, Dalemans, Dalemans, Davidson, de Haan, Duncan, Elman, Elman, Engelter, Ferrucci, Fink, Franzén-Dahlin, Haacke, Hackett, Hackett, Hartman-Maeir, Hemsley, Herrman, Hilari, Hilari, Hilari, Hilari, Hilari, Hinckley, Hinckley, Hoen, Holland, Horgan, House, Hutter, Jeffery, Jia, Jiménez Muro, Jones, Jonkman, Justin J. Needle, Jönsson, Katerina Hilari, Kauhanen, Kim, King, Kirsty L. Harrison, Kwa, Lafond, Lam, LaPointe, Legg, Lynch, Lyon, Manders, Mitchell, Mitchell, Moher, Morris, Naess, Naess, Nagayoshi, Neau, Nichols-Larsen, Niemi, Northcott, Owolabi, Owolabi, Pan, Parr, Parr, Parr, Patel, Popay, Ross, Ross, Ross, Salonen, Sarno, Sarno, Sarno, Segal, Shadden, Simmons-Mackie, Sturm, Taylor-Sarno, Teasdale, Thelander, Townend, van der Gaag, Vickers, Viitanen, Wade, Wilkinson, Worrall, Worrall   +112 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Analysis of fragment yield ratios in the nuclear phase transition [PDF]

, 2010
The critical phenomena of the liquid-gas phase transition has been investigated in the reactions 78,86Kr+58,64Ni at beam energy of 35 MeV/nucleon using the Landau free energy approach with isospin asymmetry as an order parameter.
A. Bonasera, A. Bonasera, B. C. Stein, D. V. Shetty, G. A. Souliotis, K. Hagel, K. Huang, K. Huseman, L. D. Landau, L. W. May, M. D’Agostino, R. Tripathi, S. Galanopoulos, S. J. Yennello, S. N. Soisson, S. Wuenschel, Z. Kohley   +16 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Performance Boost in Industrial Multifilamentary Nb3Sn Wires due to Radiation Induced Pinning Centers

, 2015
We report non-Cu critical current densities of 4.09 * 10^9 A/m^2 at 12 T and 2.27 * 10^9 A/m^2 at 15 T obtained from transport measurements on a Ti-alloyed RRP Nb3Sn wire after irradiation to a fast neutron fluence of 8.9 * 10^21 m^-2.
Baumgartner, T., Bottura, L., Eisterer, M., Flükiger, R., Scheuerlein, C., Weber, H. W.   +5 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source