Results 91 to 100 of about 853,111 (304)

Data Visualization with Category Theory and Geometry

This open access book provides a robust exposition of the mathematical foundations of data representation, focusing on two essential pillars of dimensionality reduction methods, namely geometry in general and Riemannian geometry in particular, and category theory. Presenting a list of examples consisting of both geometric objects and empirical datasets,
Barth, Lukas Silvester, Fahimi, Hannaneh, Joharinad, Parvaneh, Jost, Jürgen, Keck, Janis   +4 more
openaire   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Assisting reading and analysis of text documents by visualization

, 2005
The research reported here examined the use of computer generated graphics as a means to assist humans to analyse text documents which have not been subject to markup.
Maloney, Ross J.
core  

PixelQuery: Efficient Distance Range Join Query Technique for Visualization Analysis

ISPRS International Journal of Geo-Information
A distance range join query (DRJQ) is a fundamental and critical operation in spatial database queries. It identifies geographic elements within specified distance ranges.
Bo Pang, Zebang Liu, Wei Xiong, Mengyu Ma   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Ways of Seeing Data: Toward a Critical Literacy for Data Visualizations as Research Objects and Research Devices

, 2016
Gray, Bounegru, Milan and Ciuccarelli contribute towards a critical literacy for data visualizations as research objects and devices. The chapter argues for methodological reflexivity around the use of data visualizations in research as both instruments and objects of study.
Gray, Jonathan, Bounegru, Liliana, Milan, Stefania, CIUCCARELLI, PAOLO   +3 more
openaire   +5 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A survey of visual insight mining: Connecting data and insights via visualization

Visual Informatics
Insight mining transforms complex data into actionable knowledge, enabling effective decision-making across diverse domains. Given the richness and interpretative power of visualizations, visual insight mining – the process of extracting meaningful ...
Yijie Lian, Jianing Hao, Wei Zeng, Qiong Luo   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Visualization System for Operational Meterological Use

, 2022
S.525-532RASSIN is a system for professional meterological visualization that has been developed by the Fraunhofer IGD together with the German National Weather Service DWD. The software is being used in DWD's research department.
Frühauf, T., Lux, M.
core