Results 191 to 200 of about 853,111 (304)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Quantifying the AI readiness gap: An international, multidisciplinary assessment of artificial intelligence literacy in the radiation oncology community. [PDF]

Clin Transl Radiat Oncol
Malone C, Callens D, Forde E, Leech M, Cardenas C, Gooding MJ, Ryan S, Thirion P, Fitzpatrick C, O'Donovan T, Carver A, Giron IH, Browne DP, Rogerson C, McClean B, Heijmen BJM, Hanna GG, Nicholson J.   +17 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Microsurgical Clip Reconstruction of Multiple Contiguous Aneurysms of the Anterior Communicating Artery Complex: Subfrontal Exposure and Endoscopic Verification-A Case Illustration. [PDF]

Neurosurg Pract
Liu H, Oberschachtsiek L, Muhammad S.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Building youth power and environmental health literacy with environmental justice communities in rural Arizona. [PDF]

Front Public Health
Palawat K, Borkan W, Buxner S, Castañeda IM, Choi S, Choi T, Chukwuonye GN, Jaquez M, Jones M, Mariscal A, Martinez M, McBride ST, Newbauer C, Ochoa C, Quesada B, Quesada M, Quesada RN, Samorano IA, Vincent FL, Zettlemoyer A, Ramírez-Andreotta MD.   +20 more
europepmc   +1 more source

From Data to Meaning: Narrative Visualization for Critical Thinking in Semantic Web Learning

The presentation examines how narrative visualization bridges data and meaning in Digital Humanities, with a focus on Semantic Web learning. Using MELODY, a data-storytelling platform for Linked Open Data, we argue how visualizations foster critical thinking, highlight data quality issues, and support data literacy.
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Integrating molecular genetics into thyroid cancer staging: A critical perspective on personalized risk stratification in thyroidology. [PDF]

Clinics (Sao Paulo)
Sengul I, Sengul D.
europepmc   +1 more source