Results 81 to 90 of about 2,110,747 (304)

Parallel graph layout algorithm for large-scale graph data

大数据, 2016
Graph models are modeling tools which are widely used.Data visualization techniques have been widely used as intuitive data analysis tools.Graph layout algorithm is the most critical technique of graph visualization,while there are no effective parallel ...
Zhiyuan CHENG, Yubin BAO, Fangling LENG
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Scalable method for exploring phylogenetic placement uncertainty with custom visualizations using treeio and ggtree

iMeta
In metabarcoding research, such as taxon identification, phylogenetic placement plays a critical role. However, many existing phylogenetic placement methods lack comprehensive features for downstream analysis and visualization.
Meijun Chen, Xiao Luo, Shuangbin Xu, Lin Li, Junrui Li, Zijing Xie, Qianwen Wang, Yufan Liao, Bingdong Liu, Wenquan Liang, Ke Mo, Qiong Song, Xia Chen, Tommy Tsan‐Yuk Lam, Guangchuang Yu   +14 more
doaj   +1 more source

PixelQuery: Efficient Distance Range Join Query Technique for Visualization Analysis

ISPRS International Journal of Geo-Information
A distance range join query (DRJQ) is a fundamental and critical operation in spatial database queries. It identifies geographic elements within specified distance ranges.
Bo Pang, Zebang Liu, Wei Xiong, Mengyu Ma   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

A survey of visual insight mining: Connecting data and insights via visualization

Visual Informatics
Insight mining transforms complex data into actionable knowledge, enabling effective decision-making across diverse domains. Given the richness and interpretative power of visualizations, visual insight mining – the process of extracting meaningful ...
Yijie Lian, Jianing Hao, Wei Zeng, Qiong Luo   +3 more
doaj   +1 more source

Data Visualization of Educational Research on Critical Thinking and Problem-Solving Skills: A Bibliometric Analysis

, 2022
Critical thinking and problem-solving skills (CTPS) are essential for learners in the 21st century. However, designing CTPS lessons and activities for teaching students involves different aspects of interdisciplinary research. To tackle this, researchers need to understand a holistic picture of CTPS research to identify trends, theories, and research ...
timakum, tatsawan, Ammarukleart, Sujira, Wimolsittichai, Nilobon, Chuenchom, Sutthinan, Chaimin, Charochinee   +4 more
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Thinking through Visualizations: Critical Data Literacy Using Remittances

, 2016
[Chapter excerpt] "We aim to situate and critically interrogate the increasingly privileged role of data within library and information literacy outreach on college and university campuses. Following a brief discussion of data in a college context, we provide a lesson plan that adapts critical information literacy and critical data librarianship to ...
Emmelhainz, Celia, Pappas, Erin, Seale, Maura   +2 more
openaire   +1 more source

Ways of Seeing Data: Toward a Critical Literacy for Data Visualizations as Research Objects and Research Devices

, 2016
Gray, Bounegru, Milan and Ciuccarelli contribute towards a critical literacy for data visualizations as research objects and devices. The chapter argues for methodological reflexivity around the use of data visualizations in research as both instruments and objects of study.
Gray, Jonathan, Bounegru, Liliana, Milan, Stefania, CIUCCARELLI, PAOLO   +3 more
openaire   +7 more sources