Results 121 to 130 of about 1,039,545 (289)

Critical Discourse Analysis of Media Texts [PDF]

open access: yes, 2007
El volumen presenta una panorámica del Análisis Crítico del Discurso de los textos mediáticos. El Análisis Crítico del Discurso es un modelo que parte de la Lingüística Crítica, basada a su vez en la Gramática Funcional de M. A. K. Halliday.
Alonso, Isabel   +26 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

THE REPRESENTATION OF IRAN-SAUDI CONFLICT IN THE NEWSPAPERS REGARDING MINA HAJJ STAMPEDE: A CRITICAL DISCOURSE ANALYSIS ON THE ARAB NEWS AND THE TEHRAN TIMES [PDF]

open access: yes, 2016
The Hajj 2015 shows a significance flashpoint of the long-term history of tension between Tehran (Iran) and Riyadh (Saudi Arabia) regarding the Hajj: Iran and Saudi Arabiaexchanged the accusation of standing behind the tragedy of Hajj stampede in Minna ...
Al-Rawafi , Abdulkhaleq Ali Ahmed
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Discursive Constructions of the EU's Identity in the Neighbourhood: An Equal Among Equals or the Power Centre? [PDF]

open access: yes
Using critical discourse analysis, this article explores the discursive self-representations of the EU in its official documents related to the European Neighbourhood Policy.
Petr Kratochvil
core  

Стратегии исследования идеологии в критическом дискурс-анализе [PDF]

open access: yes, 2018
STRATEGIES OF IDEOLOGY INVESTIGATION IN CRITICAL DISCOURSE ANALYSIS V. BURSEVICHИсследуются основные стратегии анализа идеологии в таком междисциплинарном направлении, как критический дискурс-анализ.
Бурсевич, В. В.
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Critical Lexicography from the Perspective of Discourse Analysis [PDF]

open access: yes, 2016
词典具有描写、教导以及意识形态功能,是极其重要的社会话语,在公共、学术以及法律领域拥有几乎是无可置疑的权威。学者和法官们经常会援引词典以强调某个词或概念的意义或用法。词典的实用性使得人们通常不大想去批判它。然而,从批判的角度来看,人们应该质疑词典在词语意义上的权威性。词典事实上与权力、政治紧密联系,是意识形态的重要载体。尽管语言学家和词典学者提出了许多词典学理论,但大多是从工具论的角度来看待词典,极少将词典作为一种社会和话语现象进行研究。虽然已有一些学者研究词典中的意识形态,但采取的大多是社会学的视角 ...
陈文革
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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