Results 131 to 140 of about 127,761 (298)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A Corpus-Based Critical Discourse Analysis of English Discourse in The Jakarta Post
K@ta: A Biannual Publication on the Study of Language and LiteratureThis study examines English discourse construction in an Indonesia's English-language newspapers, The Jakarta Post. The researchers analyzed data over a 15-year period (from January 1, 2009, to December 31, 2023), focusing on the core terms of English ...
Nur Nabilah Fauziyah +1 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Higher Education Institutions’ Responses to Risk: A Critical Discourse Analysis
Increased concerns about students who present a risk to self or others have been documented in the literature since the 1990s. In particular, concern has been expressed about students who self-harm and students with mental health difficulties (for a ...
Harrison Woods, Paula L
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Educating for the future : a critical discourse analysis of the field of intercultural business communication [PDF]
, 2007 The investigation analyzes critically the discursive and generic make-up, the conceptual base and educational goals of a new interdisciplinary academic field of enquiry called Intercultural Business Communication as it is pursued in the context of the ...
Zotzmann, Karin
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Multimodal Construction of Female Looks: An Analysis of Mascara Advertisements
Dilbilim Araştırmaları Dergisi, 2016 Multimodality involves the interaction between verbal and visual components in various discourses. Advertising discourse is one of the discourses where multimodal analysis is used quite frequently.
Nazlı Baykal
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Applying Membership Categorisation Analysis to Discourse: When the 'Tripwire Critique' is not enough
, 2009 This chapter provides an outline of Membership Categorisation Analysis, exemplifies some of its applications, and argues for its significance for the agenda of critical discourse analysis.
Freebody, Peter, Freiberg, Jill
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