Results 61 to 70 of about 1,465,929 (292)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

What Is Critical Discourse Analysis?

open access: yesForum: Qualitative Social Research, 2007
In this interview, Ruth WODAK discusses the beginnings of her career, and what propelled her into critical discourse analysis. She analyses what makes critical discourse analysis "critical", distinguishes criticalness from dogmatism, but expounds upon ...
Gavin Kendall
doaj  

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Analysis of Contrast between Perincipalism and Reformism Discourses in the 10th Presidential Election inIran [PDF]

open access: yesجامعه شناسی کاربردی, 2015
علی ربانی خوراسگانی، دانشیار، گروه علوم اجتماعی دانشگاه اصفهان، ایران   محمد میرزایی، دانشجوی کارشناسی ارشد جامعه‌شناسی، دانشگاه اصفهان، ایران *      نوشتار حاضر درصدد است تا تقابل گفتمان‌های اصول‌گرایی و اصلاح‌طلبی را در دهمین دوره انتخابات ریاست جمهوری
mohammad mirzaei   +1 more
doaj  

‘Bisexual oysters’: A diachronic corpus-based critical discourse analysis of bisexual representation in The Times between 1957 and 2017

open access: yesDiscourse & Communication, 2019
Recent decades have witnessed an increase in lesbian, gay, bisexual, transgender, queer and intersex (LGBTQI) visibility in the British media. Increased representation has not been equally distributed, however, as bisexuality remains an obscured sexual ...
Mark Wilkinson
semanticscholar   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

Press, Ideological Discourse and Coup d'Etat: a Critical Discourse Analysis

open access: yesRevista Eletrônica de Ciência Administrativa, 2019
Inserted in the broader context of the historical organizational studies (Maclean, Harvey, & Clegg, 2016), the present work had as objective to analyze the Special Notebook “64 – Brazil Continues” from the Folha de São Paulo (FSP) Journal in the light of
Cynthia Adrielle da Silva Santos   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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