Results 71 to 80 of about 3,413,512 (272)

Renormalization of trace distance and multipartite entanglement close to the quantum phase transitions of one- and two-dimensional spin-chain systems

open access: yes, 2016
We investigate the quantum phase transitions of spin systems in one and two dimensions by employing trace distance and multipartite entanglement along with real-space quantum renormalization group method. As illustration examples, a one-dimensional and a
Wu, Wei, Xu, Jing-Bo
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Study on the Influence of Structural Dimensions on Plate Deflection Under Confined Blast

open access: yesApplied Sciences
The damage assessment of structures subjected to confined internal blast remains a focal point in the field of explosion. However, current research results are mostly limited to the situation where the cabin structure dimensions remain constant, and the ...
Zirui Fan   +3 more
doaj   +1 more source

The nature of most probable paths at finite temperatures

open access: yes, 2003
We determine the most probable length of paths at finite temperatures, with a preassigned end-to-end distance and a unit of energy assigned to every step on a $D$-dimensional hypercubic lattice.
Bhattacharyya, Pratip
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Effectiveness of Online Patient Safety Education on the Competency of Nurses in Intensive Care Units: A Quasi-experimental Study

open access: yesنشریه پرستاری ایران, 2022
Background & Aims: Maintaining patient safety (PS) is one of professional and ethical duties of health care providers. Nurses, as the largest professional group in the health system, have a potential and significant power in influencing the health care ...
Tahereh Najafi Ghezeljeh   +3 more
doaj  

On the extremals of the P\'olya-Szeg\H{o} inequality

open access: yes, 2014
The distance of an extremal of the P\'olya-Szeg\H{o} inequality from a translate of its symmetric decreasing rearrangement is controlled by the measure of the set of critical points.Comment: 17 pages, 3 ...
Burchard, Almut, Ferone, Adele
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Critical length parameter of HDPE and its use in fatigue lifetime predictions

open access: yesFracture and Structural Integrity
The contribution describes the fatigue lifetime predictions of polyethylene notched specimens based on the theory of critical distance. The approach uses the line method, which averages the axial stress over the critical distance.
Kamila Koz�kov�   +3 more
doaj   +5 more sources

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