Results 81 to 90 of about 3,443,652 (334)

Study on the Influence of Structural Dimensions on Plate Deflection Under Confined Blast

open access: yesApplied Sciences
The damage assessment of structures subjected to confined internal blast remains a focal point in the field of explosion. However, current research results are mostly limited to the situation where the cabin structure dimensions remain constant, and the ...
Zirui Fan   +3 more
doaj   +1 more source

Distance teaching and teaching ‘as’ distance. A critical reading of online teaching instruments during and after the pandemic

open access: yesTeoría de la Educación: Revista Interuniversitaria, 2020
This paper intends to read through a critical lens the digitalization of schooling caused by the COVID-19 epidemic. The emergency has forced European governments to close the schools and consequently, all the schooling activities have been transferred ...
Annachiara Gobbi, Federico Rovea
doaj   +1 more source

Magnetism in f electron superlattices

open access: yes, 2016
We analyze antiferromagnetism in $f$ electron superlattices. We show that the competition between the Kondo effect and the RKKY interaction in $f$ electron materials is modified by the superlattice structure.
Kawakami, Norio   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

FATIGUE LIFE PREDICTION OF NOTCHED STRUCTURE USING COMBINED CRITICAL PLANE-CRITICAL DISTANCE APPROACH (MT)

open access: yesJixie qiangdu, 2023
In engineering practice, due to various functional requirements, structures with geometric discontinuities occur widely; in addition, most structures undergo complex multiaxial loads, which drives the development of relevant theories.
LIAO Ding   +4 more
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Critical length parameter of HDPE and its use in fatigue lifetime predictions

open access: yesFracture and Structural Integrity
The contribution describes the fatigue lifetime predictions of polyethylene notched specimens based on the theory of critical distance. The approach uses the line method, which averages the axial stress over the critical distance.
Kamila Koz�kov�   +3 more
doaj   +5 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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