Results 81 to 90 of about 3,413,512 (272)
Jixie qiangdu, 2023 In engineering practice, due to various functional requirements, structures with geometric discontinuities occur widely; in addition, most structures undergo complex multiaxial loads, which drives the development of relevant theories.
LIAO Ding +4 more
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Performance of Convolution Codes Based on 60 GHz Inter-Chip Wireless Interconnection System
Dianxin kexue, 2015 In order to solve reliability problem in 60 GHz inter-chip wireless interconnection system，the performance of convolution codes was studied from the view of coding gain and energy consumption.
Xuehua Li, Siyu Shen, Yafei Wang
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Effect of Critical Distance in Digital Levelling
ComputationCritical distance concerns precise digital levelling, which has inaccurate results at a certain sighting distance. The influence of critical distance on a measured height difference has been confirmed by calibrating certain digital levels and their ...
Jana Izvoltova +2 more
doaj +1 more source
The theory of critical distances applied to problems in fracture and fatigue of bone [PDF]
Fracture and Structural Integrity, 2009 The theory of critical distances (TCD) has been applied to predict notch-based fracture and fatigue in a wide range of materials and components. The present paper describes a series of projects in which we applied this approach to human bone.
Emma Brazel, Saeid Kasiri, David Taylor
doaj
Bridging transitions for spheres and cylinders
, 2015 We study bridging transitions between spherically and cylindrically shaped particles (colloids) of radius $R$ separated by a distance $H$ that are dissolved in a bulk fluid (solvent).
Malijevský, Alexandr, Parry, Andrew O.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Path analysis from COVID-19 perceptions to psychological health: The roles of critical distance and mastery. [PDF]
Clin Psychol Psychother, 2022 Faustino B +5 more
europepmc +1 more source
The sociology of diagnosis: Critical distance
Sociology of Health & IllnessNo description ...
Bell, AV +3 more
openaire +2 more sources