Results 41 to 50 of about 388,704 (251)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Investigation on Dynamic Stability of Cement-Stabilized Expansive Soil Subgrades Subjected to Repeated Heavy-Haul Train Loads

Advances in Civil Engineering
The dynamic characteristics of the filler are intricately linked to the stability of the subgrade. In this investigation, relying on Haoji (Haolebaoji-Ji’an, China) heavy-haul railway engineering, cyclic triaxial tests were executed to scrutinize the ...
Yonghui Shang, Linrong Xu, Xiaofei Hao, Qichuan Zhu, Donghong Li   +4 more
doaj   +1 more source

Wetting deformation prediction of compacted lateritic clay subjected to dynamic loading

Journal of Rock Mechanics and Geotechnical Engineering
Rainfall infiltration and groundwater level fluctuation cause the subgrade filler to be wetted, rendering the subgrade prone to accelerated permanent deformation under long-term traffic loading.
Xuanjia Huang, Weizheng Liu, Zhaofeng Chen, Weihao Wang   +3 more
doaj   +1 more source

An experimental study of dynamic parameters of unit cell of deep mixed column-reinforced soft clay under dynamic loading

Shuiwen dizhi gongcheng dizhi, 2022
Composite soil with deep mixed column is widely used in strengthening soft soil subgrade. However, there is still a lack of understanding the dynamic characteristics of composite soil with deep mixed column and evaluating unreasonably the long-term ...
Guanbao YE, Liangkai QIN, Zhen ZHANG, Wenqiang ZHENG, Yong CHEN   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Dynamic Recrystallization Behavior and Critical Conditions of SiC_p/A1-Cu Composite

Journal of Aeronautical Materials, 2017
Using the Gleeble-1500D simulator, the high temperature plastic deformation behavior of 40%SiCP/Al-Cu composite were investigated at 350-500℃ with the strain rate of 0.01-10 s-1. The stress-strain curves were obtained during the tests.
HAO Shiming, XIE Jingpei, LIU Weining, FU Huiping, LIU Jiabin   +4 more
doaj   +1 more source

Experimental Investigations on the Effects of Fatigue Crack in Urban Metro Welded Bogie Frame

Applied Sciences, 2020
The welded bogie frame is the critical safety part of the urban metro vehicle. This paper focuses on finding out the factors inducing the fatigue cracks initiated from the positioning block weld toe of metro bogie frame.
Wenjing Wang, Jinyi Bai, Shengchuan Wu, Jing Zheng, Pingyu Zhou   +4 more
doaj   +1 more source

Mechanism and prevention of rock burst induced by horizontal sublevel mining of a steeply inclined extra-thick coal seam

Meikuang Anquan, 2021
In order to prevent the rock burst caused by horizontal sublevel mining of a steeply inclined extra-thick coal seam, the mechanism of rock burst induced by the superposition of dynamic and static loads and the corresponding prevention measures were ...
WANG Zhengyi, DOU Linming, HE Jiang, CAO Jinrong
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dynamic mechanical characteristics of deep Jinping marble in complex stress environments

Journal of Rock Mechanics and Geotechnical Engineering
To reveal the dynamic mechanical characteristics of deep rocks, a series of impact tests under triaxial static stress states corresponding to depths of 300–2400 m were conducted.
Chendi Lou, Heping Xie, Ru Zhang, Hai Ren, Hao Luo, Kun Xiao, Yuan Peng, Qiang Tan, Li Ren   +8 more
doaj   +1 more source