Results 81 to 90 of about 5,911,268 (324)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Magnetic Excitations of Stripes near a Quantum Critical Point

open access: yesPhysical Review Letters, 2006
We calculate the dynamical spin structure factor of spin waves for weakly coupled stripes. At low energy, the spin wave cone intensity is strongly peaked on the inner branches. As energy is increased, there is a saddlepoint followed by a square-shaped continuum rotated 45 degree from the low energy peaks.
Yao, D. X.   +2 more
openaire   +5 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Simple analytical method for predicting the sloshing motion in a rectangular pool

open access: yesNuclear Engineering and Technology, 2020
Predicting the sloshing motion of a coolant during a seismic assessment of a rectangular spent fuel pool is of critical concern. Linear theory, which provides a simple analytical method, has been used to predict the sloshing motion in rectangular pools ...
Won Man Park   +7 more
doaj   +1 more source

Excitation Spectra of Disordered Dimer Magnets Near Quantum Criticality [PDF]

open access: yesPhysical Review Letters, 2013
For coupled-dimer magnets with quenched disorder, we introduce a generalization of the bond-operator method, appropriate to describe both singlet and magnetically ordered phases. This allows for a numerical calculation of the magnetic excitations at all energies across the phase diagram, including the strongly inhomogeneous Griffiths regime near ...
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Charge/mass yields in the fission of highly excited heavy actinides

open access: yesEPJ Web of Conferences, 2018
The charge (mass) distributions of fission fragments resulting from low- and high-energy fission of the isotopes of Fm and No are studied with the statistical scission-point fission model.
Paşca H.   +3 more
doaj   +1 more source

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