Results 81 to 90 of about 5,212,253 (358)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Off-critical parafermions and the winding angle distribution of the O($n$) model

, 2012
Using an off-critical deformation of the identity of Duminil-Copin and Smirnov, we prove a relationship between half-plane surface critical exponents $\gamma_1$ and $\gamma_{11}$ as well as wedge critical exponents $\gamma_2(\alpha)$ and $\gamma_{21 ...
de Gier, Jan, Guttmann, Anthony J., Lee, Alexander, Price, Andrew Elvey   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Critical exponents in Ising spin glasses

, 1997
We determine accurate values of ordering temperatures and critical exponents for Ising Spin Glass transitions in dimension 4, using a combination of finite size scaling and non-equilibrium scaling techniques.
A. Zippelius, A.T. Ogielski, D. Badoni, D.A. Huse, G. Parisi, H. Sompolinsky, H.K. Janssen, I. A. Campbell, J. Kisker, J. Wang, J.E. Green, L. Bernardi, L. Klein, L. Schulke, L. W. Bernardi, L.W. Bernardi, R.N. Bhatt, R.N. Bhatt, R.R.P. Singh, R.R.P. Singh, S. Prakash, Z. Li   +21 more
core   +1 more source

On a p-Laplacian system with critical Hardy–Sobolev exponents and critical Sobolev exponents [PDF]

Ukrainian Mathematical Journal, 2012
In this paper, the existence results of positive solutions for the semiliner elliptic system \[ \begin{cases} -\text{div} (|\nabla u_i|^{p-2} \nabla u_i) - \mu \frac{|u_i|^{p-2}u_i}{|x|^p} \\ = \frac{1}{p^*} F_{u_i}(u_1,\ldots,u_k) + \frac{|u_i|^{p^*(t)-2}u_i}{|x|^t} + \lambda \frac{|u_i|^{p-2}u_i}{|x|^s}, \quad x \in \Omega, \\ u_i=0 \quad \text{on} \;
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Small perturbations of critical nonlocal equations with variable exponents

Demonstratio Mathematica, 2023
In this article, we are concerned with the following critical nonlocal equation with variable exponents: (−Δ)p(x,y)su=λf(x,u)+∣u∣q(x)−2uinΩ,u=0inRN\Ω,\left\{\begin{array}{ll}{\left(-\Delta )}_{p\left(x,y)}^{s}u=\lambda f\left(x,u)+{| u| }^{q\left(x)-2}u&
Tao Lulu, He Rui, Liang Sihua
doaj   +1 more source

Critical Exponents from AdS/CFT with Flavor [PDF]

, 2009
We use the AdS/CFT correspondence to study the thermodynamics of massive N=2 supersymmetric hypermultiplet flavor fields coupled to N=4 supersymmetric SU(Nc) Yang-Mills theory, formulated on curved four-manifolds, in the limits of large Nc and large 't ...
A. Karch, A. Karch, A. Karch, A. Karch, Andreas Karch, Andy O'Bannon, C. Fefferman, C. Hoyos-Badajoz, D. Mateos, D. Mateos, E. Witten, E. Witten, J. Erdmenger, J.M. Maldacena, Laurence G Yaffe, M. Kruczenski, P. Kovtun, S. Kobayashi, T. Albash, T. Albash, T. Faulkner, V.G. Filev, V.G. Filev, V.G. Filev, V.G. Filev, V.N. Gribov   +25 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Lyapunov exponents and phase transition of Hayward AdS black hole

European Physical Journal C: Particles and Fields
In this paper, we study the relationship between the phase transition and Lyapunov exponents for 4D Hayward anti-de Sitter (AdS) black hole. We consider the motion of massless and massive particles around an unstable circular orbit of the Hayward AdS ...
Naba Jyoti Gogoi, Saumen Acharjee, Prabwal Phukon   +2 more
doaj   +1 more source