Results 101 to 110 of about 12,861,561 (372)
The spinorial energy functional: solutions of the gradient flow on Berger spheres
We study the negative gradient flow of the spinorial energy functional (introduced by Ammann, Wei{\ss}, and Witt) on 3-dimensional Berger spheres. For a certain class of spinors we show that the Berger spheres collapse to a 2-dimensional sphere. Moreover,
Wittmann, Johannes
core +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
CFD Analyses of Density Gradients under Conditions of Supersonic Flow at Low Pressures
This paper deals with CFD analyses of the difference in the nature of the shock waves in supersonic flow under atmospheric pressure and pressure conditions at the boundary of continuum mechanics for electron microscopy.
Robert Bayer+5 more
doaj +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
Deformation based circulating tumor cell (CTC) microchips are a representative diagnostic device for early cancer detection. This type of device usually involves a process of CTC trapping in a confined microgeometry. Further understanding of the CTC flow
Chen, Xiaolin, Xu, Jie, Zhang, Zhifeng
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A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
This paper involves characterizations of a class of continuous flows. The flows considered are those in which the positive prolongation of each point coincides with the trajectory through the point.
Ramon Mogollon
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Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil+5 more
wiley +1 more source
Flow patterns and critical criteria of thermally stratified shear flow in braided rivers
Flow characteristics of thermally stratified shear flow in braided rivers are particularly complicated and poorly understood. In this study, a series of typical flow patterns was examined and their critical criteria were determined.
Li Gu+5 more
doaj +1 more source