Results 101 to 110 of about 4,116,169 (343)

Improving parallel program performance using critical path analysis [PDF]

open access: yes, 1989
A programming tool that performs analysis of critical paths for parallel programs has been developed. This tool determines the critical path for the program as scheduled onto a parallel computer with P processing elements, the critical path for the ...
Bic, Lubomir   +2 more
core  

The spinorial energy functional: solutions of the gradient flow on Berger spheres

open access: yes, 2016
We study the negative gradient flow of the spinorial energy functional (introduced by Ammann, Wei{\ss}, and Witt) on 3-dimensional Berger spheres. For a certain class of spinors we show that the Berger spheres collapse to a 2-dimensional sphere. Moreover,
Wittmann, Johannes
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Critical Flow Restricting Orifices [PDF]

open access: yes, 1988
The installation of flow restricting orifices in both the nitrogen gas and instrument air supply lines in the D-Zero Building limits the flow available to the various users. These orifices are strategically positioned along the lines such that no one user can monopolize the gas supply and deprive others of their flow required to operate.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

On a class of continous flow

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1980
This paper involves characterizations of a class of continuous flows. The flows considered are those in which the positive prolongation of each point coincides with the trajectory through the point.
Ramon Mogollon
doaj   +1 more source

The fund-flow approach. A critical survey [PDF]

open access: yes
The fund-flow approach to production theory was first proposed by Nicholas Georgescu-Roegen almost half a century ago. Since then, from time to time it has received attention, but, probably because of its analytical complexity and difficulty to deliver ...
Giuseppe Vittucci Marzetti
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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