Results 111 to 120 of about 1,563,368 (312)

Mechanism analysis on fluidelastic instability of tube bundles in considering of cross-flow effects

open access: yesNuclear Engineering and Technology, 2019
Fluidelastic instability is a key issue in steam generator tube bundles subjected in cross-flow. With a low flow velocity, a large amplitude vibration of the tube observed by many researchers.
Jiang Lai   +3 more
doaj   +1 more source

Roughness-Induced Critical Phenomena in a Turbulent Flow [PDF]

open access: yesPhysical Review Letters, 2006
I present empirical evidence that turbulent flows are closely analogous to critical phenomena, from a reanalysis of friction factor measurements in rough pipes. The data collapse found here corresponds to Widom scaling near critical points, and implies that a full understanding of turbulence requires explicit accounting for boundary roughness.
openaire   +3 more sources

Patient journey modelling : a critical enabler for healthcare innovation

open access: yes, 2011
This is a workshop presented by Dr Joanne Curry for IQPC - Optimising Patient ...
Curry, Joanne (R9655)
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Choked Flow Characteristics of Subcritical Refrigerant Flowing Through Converging-Diverging Nozzles

open access: yesEntropy, 2014
This paper presents the experimental results the choked flow characteristics of a subcritical refrigerant through a converging-diverging nozzle. A test nozzle with a throat diameter of 2 mm was designed and developed.
Zhenying Zhang   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Large-eddy simulation of flow over a circular cylinder in the sub-critical regime

open access: yes, 2017
We present wall-resolved, large-eddy simulation (LES) of flow over a circular cylinder up to ReD = 105, based on the cylinder diameter D, in the subcritical regime.
Pullin, D. I., Samtaney, R., Cheng, W.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Flow-critical graphs

open access: yes
52 pages, in Journal of Graph ...
Árnadóttir, Arnbjörg Soffía   +5 more
openaire   +2 more sources

Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure

open access: yes, 2016
Publisher Copyright: © 2016 Roca et al.High flow nasal cannula (HFNC) supportive therapy has emerged as a safe, useful therapy in patients with respiratory failure, improving oxygenation and comfort.
Spanish Multidisciplinary Group of High Flow Supportive Therapy in Adults (HiSpaFlow)
core   +1 more source

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