Results 101 to 110 of about 1,563,368 (312)
Flow patterns and heat transfer for flow boiling in small to micro diameter tubes
, 2008 An overview of the recent developments in the study of flow patterns and boiling heat transfer in small to micro diameter tubes is presented. The latest results of a long-term study of flow boiling of R134a in five vertical stainless steel tubes of ...
Karayiannis, TG +3 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A study on required volume of superconducting element for flux flow resistance type fault current limiter [PDF]
, 2003 We have proposed a fault current limiter (FCL) suppressing an overcurrent only by a flux flowresistance of a high temperature superconductor (HTS). If the fault current is interrupted within an allowable time Tα after the fault occurs, the flux flow ...
Goto, M. +4 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Flow boiling of R134a in vertical mini-diameter tubes
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 21/03/2011.The current study is a part of a long term experimental project devoted to investigate flow boiling heat transfer, pressure drop and flow ...
Mahmoud M, Mohamed M
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Flow Separation in Rocket Nozzles, a Simple Criteria
, 2005 Cold and hot flow tests were conducted to investigate the flow separation in rocket nozzles. The results are presented. A separation data base including a wide range of literature data is established to evaluate the influence of propellant combination ...
Ralf Stark, Stark, Ralf
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Revista EIA, 2008 Uno de los objetivos de un curso básico de hidráulica del flujo libre en canales es el análisis de perfiles del flujo gradualmente variado. Este trabajo proporciona una estrategia de enseñanza-aprendizaje que puede mejorar la práctica universitaria ...
Francisco Jaime Mejía
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source