Results 111 to 120 of about 12,861,561 (372)

Two-phase choked flow of subcooled oxygen and nitrogen [PDF]

open access: yes
Data are presented for two-phase critical flow through nozzles. Test results from two converging-diverging nozzles and two separate test facilities are in excellent agreement.
Barrows, R. F.   +2 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Transonic flow field in critical flow Venturi nozzle

open access: yesApplied and Computational Mechanics
In this paper, theoretical and numerical analysis of a transonic flow field of critical flow Venturi nozzles according to the ISO 9300 standard is performed. Deviations of the flow field from an estimate based on one dimensionality are clarified.
Kreuzová T.
doaj   +1 more source

Snarks and Flow-Critical Graphs

open access: yesElectronic Notes in Discrete Mathematics, 2013
Abstract It is well-known that a 2-edge-connected cubic graph has a 3-edge-colouring if and only if it has a 4-flow. Snarks are usually regarded to be, in some sense, the minimal cubic graphs without a 3-edge-colouring. We defined the notion of 4-flow-critical graphs as an alternative concept towards minimal graphs.
Cândida Nunes da Silva   +2 more
openaire   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

RELACIÓN DE LAS CURVAS DE ENERGÍA ESPECÍFICA Y PENDIENTE DE FRICCIÓN CON LAS ZONAS DE FLUJO LIBRE EN CANALES

open access: yesRevista EIA, 2008
Uno de los objetivos de un curso básico de hidráulica del flujo libre en canales es el análisis de perfiles del flujo gradualmente variado. Este trabajo proporciona una estrategia de enseñanza-aprendizaje que puede mejorar la práctica universitaria ...
Francisco Jaime Mejía
doaj  

Mechanism analysis on fluidelastic instability of tube bundles in considering of cross-flow effects

open access: yesNuclear Engineering and Technology, 2019
Fluidelastic instability is a key issue in steam generator tube bundles subjected in cross-flow. With a low flow velocity, a large amplitude vibration of the tube observed by many researchers.
Jiang Lai   +3 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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