Results 151 to 160 of about 12,861,561 (372)

An approach to optimum subsonic inlet design [PDF]

open access: yes
Inlet operating requirements are compared with estimated inlet separation characteristics to identify the most critical inlet operating condition. This critical condition is taken to be the design point and is defined by the values of inlet mass flow ...
Diedrich, J. H.   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Spatial evolution of nonlinear acoustic mode instabilities on hypersonic boundary layers [PDF]

open access: yes
The effects are considered of strong critical layer nonlinearity on the spatial evolution of an initially linear acoustic mode instability wave on a hypersonic flat plate boundary layer.
Goldstein, M. E., Wundrow, D. W.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Critical assessment of turbulence prediction in square duct flow

open access: yesNuclear Engineering and Technology
Prandtl's secondary flows of the second kind occur when turbulent fluid flows through straight, non-circular geometries, even with a uniform axial inlet flow.
Abdelrahman Irbai   +3 more
doaj   +1 more source

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